Eucalyptusdimers A-C, Dimeric Phloroglucinol Phellandrene Meroterpenoids from Eucalyptus robusta
Qin, Xu-Jie1,2; Feng, Mi-Yan1,2; Liu, Hui1,2; Ni, Wei1,2; Rauwolf, Tyler3; Porco, John A., Jr.3; Yan, Huan1,2; He, Li4; Liu, Hai-Yang1,2
刊名ORGANIC LETTERS
2018-08-17
卷号20期号:16页码:5066-5070
ISSN号1523-7060
DOI10.1021/acs.orglett.8b02259
英文摘要

Eucalyptusdimers A-C, three dimeric phellandrene-derived meroterpenoids featuring an unprecedented, fused skeleton between two phellandrene and two acylphloroglucinol subunits, along with one biogenetically related intermediate, (+)-eucalyprobusone A, were isolated from the fruits of Eucalyptus robusta. Their structures and absolute configurations were elucidated using spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. The isolated meroterpenoids were evaluated for their anti-inflammatory, acetylcholinesterase inhibitory, and protein tyrosine phosphatase 1B inhibitory effects.

资助项目National Natural Science Foundation of China[31570363] ; National Natural Science Foundation of China[31600283] ; National Natural Science Foundation of China[31770391] ; National Institutes of Health[R35 GM-118173] ; Major Bio-Medical Project of Yunnan Province[2017AB001] ; Major Bio-Medical Project of Yunnan Province[2018ZF005] ; Natural Science Foundation of Yunnan Province[2017FB128] ; Key Research and Development Plan of Yunnan Province-Special Project of Science and Technology in Yunnan Province[20171B007] ; Innovation Team of the Ministry of Education[IRT-17R49] ; Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China[P2017-ZZ04] ; Kunming Institute of Botany, Chinese Academy of Sciences
WOS研究方向Chemistry
语种英语
出版者AMER CHEMICAL SOC
WOS记录号WOS:000442454900078
资助机构National Natural Science Foundation of China ; National Institutes of Health ; Major Bio-Medical Project of Yunnan Province ; Natural Science Foundation of Yunnan Province ; Key Research and Development Plan of Yunnan Province-Special Project of Science and Technology in Yunnan Province ; Innovation Team of the Ministry of Education ; Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China ; Kunming Institute of Botany, Chinese Academy of Sciences
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/62215]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者Liu, Hai-Yang
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
3.Boston Univ, CMD, BU, Dept Chem, 590 Commonwealth Ave, Boston, MA 02215 USA
4.Kunming Med Univ, Affiliated Hosp 1, Dept Dermatol, Kunming 650032, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Qin, Xu-Jie,Feng, Mi-Yan,Liu, Hui,et al. Eucalyptusdimers A-C, Dimeric Phloroglucinol Phellandrene Meroterpenoids from Eucalyptus robusta[J]. ORGANIC LETTERS,2018,20(16):5066-5070.
APA Qin, Xu-Jie.,Feng, Mi-Yan.,Liu, Hui.,Ni, Wei.,Rauwolf, Tyler.,...&Liu, Hai-Yang.(2018).Eucalyptusdimers A-C, Dimeric Phloroglucinol Phellandrene Meroterpenoids from Eucalyptus robusta.ORGANIC LETTERS,20(16),5066-5070.
MLA Qin, Xu-Jie,et al."Eucalyptusdimers A-C, Dimeric Phloroglucinol Phellandrene Meroterpenoids from Eucalyptus robusta".ORGANIC LETTERS 20.16(2018):5066-5070.
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