Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy
	Yang, Yang1,3 ; Yan, Yong-Ming 1; Wei, Wei 4; Luo, Jie 1; Zhang, Lan-Sheng 1; Zhou, Xiao-Jiang 4; Wang, Peng-Cheng 1; Yang, Yong-Xun 2; Cheng, Yong-Xian 1
刊名	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
	2013-07-01
卷号	23 期号:13 页码:3905-3909
关键词	Anthraquinone Oxanthrone C-glycoside Diabetic Nephropathy Rumex Endophytic Aspergillus Fumigatus
ISSN号	0960-894X
通讯作者	Cheng, YX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China. ; yxcheng@mail.kib.ac.cn
文献子类	Article
英文摘要	Two new oxanthrone C-glycosides, patientosides A (14) and B (15), together with three known ones (11-13), were isolated from Rumex patientia. Their structures were identified on the basis of spectroscopic methods. The absolute configuration for 14 and 15 were deduced by analysis of their CD spectra and comparison with those of known similar compounds. Compounds 11-15, and 14 known anthraquinones (1-4, 6-10, 16-20) previously isolated from Rumex nepalensis, Rumex hastatus, and endophytic Aspergillus fumigatus, respectively, as well as a commercially available compound rhein (5) were evaluated for their inhibitory effects on IL-6 and extracellular matrix production in mesangial cells. (c) 2013 Elsevier Ltd. All rights reserved.
学科主题	Chemistry, Medicinal ; Chemistry, Organic
WOS关键词	GLUCOSIDES ; ROOTS
WOS研究方向	Pharmacology & Pharmacy ; Chemistry
语种	英语
WOS记录号	WOS:000320702900045
资助机构	National Natural Science Foundation of China [20972165]; Key Project for Drug Innovation from the Ministry of Science and Technology of China [2012ZX09103-201-052]; Open Research Fund of State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources; Key Research Program of the Chinese Academy of Sciences [KSZD-EW-Z-004]; Project of Natural Compound Library Construction from Chinese Academy of Sciences [KSCX2-EW-R-15]
公开日期	2013-10-16
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/16757]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 610075, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 4.Hunan Univ Chinese Med, Coll Pharm, Changsha 410208, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yang,Yan, Yong-Ming,Wei, Wei,et al. Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2013,23(13):3905-3909.
APA	Yang, Yang.,Yan, Yong-Ming.,Wei, Wei.,Luo, Jie.,Zhang, Lan-Sheng.,...&Cheng, Yong-Xian.(2013).Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,23(13),3905-3909.
MLA	Yang, Yang,et al."Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 23.13(2013):3905-3909.