Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma
Zou, Qing-Feng1; Du, Ji-Ke1; Zhang, Hua2; Wang, Hong-Bo2; Hu, Ze-Dong4; Chen, Shu-Peng2; Du, Yong2; Li, Man-Zhi2; Xie, Dan2; Zou, Juan3
刊名JOURNAL OF TRANSLATIONAL MEDICINE
2013-08-28
卷号11期号:1页码:200
关键词Longikaurin a (Lk-a) Apoptosis Caspase Nasopharyngeal Carcinoma
ISSN号1479-5876
通讯作者Pu, JX (reprint author), Chinese Acad Sci, Kunming Inst Bot, Kunming, Yunnan, Peoples R China. ; pujianxin@mail.kib.ac.cn ; zengmsh@sysucc.org.cn
文献子类Article
英文摘要

Background: Longikaurin A is a natural ent-kaurene diterpenoid isolated from Isodon genus. The ent-kaurene diterpenoids isolated from medicinal plants have been shown to have anti-disease effects. The present study was designed to examine the anti-tumour effects of longikaurin A (LK-A) in nasopharyngeal carcinoma in vitro and in vivo.

学科主题Medicine, Research & Experimental
WOS关键词CASPASE-DEPENDENT PATHWAY ; CELL-DEATH ; SIGNALING PATHWAYS ; IN-VIVO ; APOPTOSIS ; ORIDONIN ; PROTEIN ; ACTIVATION ; INHIBITOR ; MITOCHONDRIAL
WOS研究方向Research & Experimental Medicine
语种英语
WOS记录号WOS:000324342600001
资助机构Ministry of Science and Technology of China [2012CB967003] ; National Natural Science Funds for Distinguished Young Scholars [81025014] ; National Natural Science Foundation of China [81172939, 91019015]
公开日期2013-10-16
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/16689]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Guangzhou Med Univ, Affiliated Tumor Hosp, Sect Internal Med 3, Guangzhou, Guangdong, Peoples R China
2.Sun Yat Sen Univ, Ctr Canc, Dept Expt Res, State Key Lab Oncol South China, Guangzhou 510275, Guangdong, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, Kunming, Yunnan, Peoples R China
4.Kunming Med Univ, Affiliated Hosp 3, Dept Head & Neck Surg, Kunming, Peoples R China
推荐引用方式
GB/T 7714
Zou, Qing-Feng,Du, Ji-Ke,Zhang, Hua,et al. Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma[J]. JOURNAL OF TRANSLATIONAL MEDICINE,2013,11(1):200.
APA Zou, Qing-Feng.,Du, Ji-Ke.,Zhang, Hua.,Wang, Hong-Bo.,Hu, Ze-Dong.,...&Zeng, Mu-Sheng.(2013).Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma.JOURNAL OF TRANSLATIONAL MEDICINE,11(1),200.
MLA Zou, Qing-Feng,et al."Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma".JOURNAL OF TRANSLATIONAL MEDICINE 11.1(2013):200.
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