Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry
Jiang, B; Kronenberg, F; Qiu, MH; Kennelly, EJ
刊名JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
2006-05-03
卷号54期号:9页码:3242-3253
关键词Black Cohosh Dietary Supplements Quality Control Triterpene Glycosides Phenolic Constituents Formononetin Actaea Racemosa Cimicifuga Racemosa Asian Actaea Species
ISSN号0021-8561
DOI10.1021/jf0606149
文献子类Article
英文摘要Black cohosh (Actaea racemosa L., syn. Cimicifuga racemosa L.) has become increasingly popular as a dietary supplement in the United States for the treatment of symptoms related to menopause, but the botanical authenticity of most products containing black cohosh has not been evaluated, nor is manufacturing highly regulated in the United States. In this study, 11 black cohosh products were analyzed for triterpene glycosides, phenolic constituents, and formononetin by high-performance liquid chromatography-photodiode array detection and a new selected ion monitoring liquid chromatographymass spectrometry method. Three of the 11 products were found to contain the marker compound cimifugin and not cimiracemoside C, thereby indicating that these plants contain Asian Actaea instead of black cohosh. One product contained both black cohosh and an Asian Actaea species. For the products containing only black cohosh, there was significant product-to-product variability in the amounts of the selected triterpene glycosides and phenolic constituents, and as expected, no formononetin was detected.
学科主题Agriculture ; Multidisciplinary ; Chemistry ; Applied ; Food Science & Technology
WOS关键词CIMICIFUGA-RACEMOSA ; TRITERPENE GLYCOSIDES ; MENOPAUSAL SYMPTOMS ; ESTROGENIC ACTIVITY ; BREAST-CANCER ; HOT FLASHES ; WOMEN ; EXTRACTS ; THERAPY ; RHIZOMA
WOS研究方向Agriculture ; Chemistry ; Food Science & Technology
语种英语
WOS记录号WOS:000237524900013
公开日期2011-11-24
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/1581]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.CUNY Herbert H Lehman Coll, Dept Biol Sci, Bronx, NY 10468 USA
2.CUNY, Grad Ctr, Bronx, NY 10468 USA
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource W China, Kunming 650204, Yunnan, Peoples R China
4.Columbia Univ, Coll Phys & Surg, Richard & Hinda Rosenthal Ctr Complementary & Alt, Dept Rehabil Med, New York, NY 10032 USA
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Jiang, B,Kronenberg, F,Qiu, MH,et al. Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2006,54(9):3242-3253.
APA Jiang, B,Kronenberg, F,Qiu, MH,&Kennelly, EJ.(2006).Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,54(9),3242-3253.
MLA Jiang, B,et al."Evaluation of the botanical authenticity and phytochemical profile of black cohosh products by high-performance liquid chromatography with selected ion monitoring liquid chromatography-mass spectrometry".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 54.9(2006):3242-3253.
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