Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola
Fang, LZ; Qing, C; Shao, HJ; Yang, YD; Dong, ZJ; Wang, F; Zhao, W; Yang, WQ; Liu, JK
刊名JOURNAL OF ANTIBIOTICS
2006-06-01
卷号59期号:6页码:351-354
关键词Hypocrellin d Perylenequinone Shiraia Bambusicola Pigment Ascomycete Cytotoxicity
ISSN号0021-8820
文献子类Article
英文摘要A fungal pigment, hypocrellin D (1), together with three known perylenequinone derivatives hypocrellin A (2), B (3) and C (4), was isolated from the fruiting bodies of Shiraia bambusicola. Its structure was elucidated on the basis of spectral data including 2D NMR experiments. Hypocrellin D (1) significantly inhibited the growth of tumor cell lines Bel-7721, A-549 and Anip-973 with IC50 values of 1.8, 8.8, 38.4, mu g/ml, respectively.
学科主题Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS关键词SECONDARY MOLD METABOLITES ; PERYLENEQUINONES ; ASSAY
WOS研究方向Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000238785700004
公开日期2011-11-24
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/1569]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resource W China, Kunming 650204, Peoples R China
2.Kunming Med Coll, Kunming 650031, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 1000439, Peoples R China
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GB/T 7714
Fang, LZ,Qing, C,Shao, HJ,et al. Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola[J]. JOURNAL OF ANTIBIOTICS,2006,59(6):351-354.
APA Fang, LZ.,Qing, C.,Shao, HJ.,Yang, YD.,Dong, ZJ.,...&Liu, JK.(2006).Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola.JOURNAL OF ANTIBIOTICS,59(6),351-354.
MLA Fang, LZ,et al."Hypocrellin D, a cytotoxic fungal pigment from fruiting bodies of the ascomycete Shiraia bambusicola".JOURNAL OF ANTIBIOTICS 59.6(2006):351-354.
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