Indole alkaloids from Ervatamia chinensis

doi:10.1016/j.phytochem.2011.11.002

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Indole alkaloids from Ervatamia chinensis
	Guo, Ling-Li1,2 ; He, Hong-Ping 1; Di, Ying-Tong1 ; Li, Shi-Fei 1; Cheng, Yuan-Yuan 1; Yang, Wei 1; Li, Yan1 ; Yu, Jian-Ping 2; Zhang, Yu1 ; Hao, Xiao-Jiang1
刊名	PHYTOCHEMISTRY
	2012-02-01
卷号	74 页码:140-145
关键词	Ervatamia Chinensis Apocynaceae Bisindole Alkaloids Ervachinines A-d Cytotoxicity
ISSN号	0031-9422
DOI	10.1016/j.phytochem.2011.11.002
通讯作者	Zhang, Y (reprint author), Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China, zhangyu@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn
文献子类	Article
英文摘要	Four vobasinyl-ibogan type bisindole alkaloids, ervachinines A-D (1-4), along with 12 known terpenoid indole alkaloids, were isolated from the whole plant of Ervatamia chinensis. Their structures were elucidated by analysis of spectroscopic data, including 1D and 2D NMR, and the absolute configurations of 1-4 were determined by CD exciton chirality method. All of the compounds were evaluated for in vitro cytotoxicity against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480. Bisindole alkaloids 1-6 exhibited inhibitory effects, with IC50 values comparable to those of cisplatin. (C) 2011 Elsevier Ltd. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Plant Sciences
WOS关键词	TROPICAL MEDICINAL-PLANTS ; CONSTITUENTS ; ELEGANS
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences
语种	英语
WOS记录号	WOS:000300815700015
资助机构	National Basic Research Program of China (973 Program)[2009CB940900, 2009CB522300]; National Natural Science Foundation of China[31100259, 30830114]; Young Academic and Technical Leader Raising Foundation of Yunnan Province[20090072]
公开日期	2012-06-07
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/10369]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 2.Guizhou Univ, Coll Life Sci, Guiyang 550025, Peoples R China
推荐引用方式 GB/T 7714	Guo, Ling-Li,He, Hong-Ping,Di, Ying-Tong,et al. Indole alkaloids from Ervatamia chinensis[J]. PHYTOCHEMISTRY,2012,74:140-145.
APA	Guo, Ling-Li.,He, Hong-Ping.,Di, Ying-Tong.,Li, Shi-Fei.,Cheng, Yuan-Yuan.,...&Hao, Xiao-Jiang.(2012).Indole alkaloids from Ervatamia chinensis.PHYTOCHEMISTRY,74,140-145.
MLA	Guo, Ling-Li,et al."Indole alkaloids from Ervatamia chinensis".PHYTOCHEMISTRY 74(2012):140-145.