Two novel diterpenoids from Isodon rubescens var. lushanensis

doi:10.1016/j.tetlet.2010.06.015

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Two novel diterpenoids from Isodon rubescens var. lushanensis
	Zhang, Hai-Bo 1,2; Du, Xue 1; Pu, Jian-Xin1 ; Wang, Yuan-Yuan 1; He, Fei 1; Zhao, Yong 1; Li, Xiao-Nian 1; Luo, Xiao 1; Xiao, Wei-Lie 1; Li, Yan1
刊名	TETRAHEDRON LETTERS
	2010-08-11
卷号	51 期号:32 页码:4225-4228
关键词	Isodon Rubescens Var. Lushanensis Diterpenoid Luanchunin a Luanchunin b
ISSN号	0040-4039
DOI	10.1016/j.tetlet.2010.06.015
文献子类	Article
英文摘要	Two novel diterpenoids, luanchunins A (1) and B (2), along with their precursor, kamebakaurin (3), had been isolated from the stems and leaves of Isodon rubescens var. lushanensis. Their structures were elucidated on the basis of extensive spectroscopic analyses. Compounds 1 and 2 showed potent cytotoxic activity against HL-60 with IC(50) values of 4.81 mu M and 3.52 mu M, respectively. Plausible pathways for the biosynthesis of 1 and 2 were also postulated. (C) 2010 Elsevier Ltd. All rights reserved.
学科主题	Chemistry ; Organic
WOS关键词	ENT-KAURANE DITERPENOIDS ; ERIOCALYX ; SKELETON
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000280345800019
资助机构	NSFC [30772637, 30830119]; NSFC-Joint Foundation of Yunnan Province [U0832602]; Major State Basic Research Development Program of China [2009CB522300, 2009CB940900]; Natural Science Foundation of Yunnan Province [2008CD162]; CAS [KSCX2-YW-R-25]
公开日期	2011-11-24
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/1499]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Hai-Bo,Du, Xue,Pu, Jian-Xin,et al. Two novel diterpenoids from Isodon rubescens var. lushanensis[J]. TETRAHEDRON LETTERS,2010,51(32):4225-4228.
APA	Zhang, Hai-Bo.,Du, Xue.,Pu, Jian-Xin.,Wang, Yuan-Yuan.,He, Fei.,...&Sun, Han-Dong.(2010).Two novel diterpenoids from Isodon rubescens var. lushanensis.TETRAHEDRON LETTERS,51(32),4225-4228.
MLA	Zhang, Hai-Bo,et al."Two novel diterpenoids from Isodon rubescens var. lushanensis".TETRAHEDRON LETTERS 51.32(2010):4225-4228.