Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: From single molecules to living cells

CORC > 沈阳自动化研究所 > 中国科学院沈阳自动化研究所 > 机器人学研究室

	Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: From single molecules to living cells
	Wang YC(王越超); Dang D(党丹); Xi N(席宁); Li M(李密); Liu LQ(刘连庆)
刊名	Nanoscale
	2017
卷号	9 期号:45 页码:17643-17666
ISSN号	2040-3364
通讯作者	Li M(李密) ; Liu LQ(刘连庆)
产权排序	1
中文摘要	Due to the lack of adequate tools for observation, native molecular behaviors at the nanoscale have been poorly understood. The advent of atomic force microscopy (AFM) provides an exciting instrument for investigating physiological processes on individual living cells with molecular resolution, which attracts the attention of worldwide researchers. In the past few decades, AFM has been widely utilized to investigate molecular activities on diverse biological interfaces, and the performances and functions of AFM have also been continuously improved, greatly improving our understanding of the behaviors of single molecules in action and demonstrating the important role of AFM in addressing biological issues with unprecedented spatiotemporal resolution. In this article, we review the related techniques and recent progress about applying AFM to characterize biomolecular systems in situ from single molecules to living cells. The challenges and future directions are also discussed.
收录类别	SCI ; EI
语种	英语
WOS记录号	WOS:000416825000001
内容类型	期刊论文
源URL	[http://ir.sia.cn/handle/173321/21253]
专题	沈阳自动化研究所_机器人学研究室
作者单位	1.Department of Industrial and Manufacturing Systems Engineering, University of Hong Kong, Hong Kong 2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China 3.School of Medical Devices, Shenyang Pharmaceutical University, Shenyang 110016, China
推荐引用方式 GB/T 7714	Wang YC,Dang D,Xi N,et al. Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: From single molecules to living cells[J]. Nanoscale,2017,9(45):17643-17666.
APA	Wang YC,Dang D,Xi N,Li M,&Liu LQ.(2017).Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: From single molecules to living cells.Nanoscale,9(45),17643-17666.
MLA	Wang YC,et al."Nanoscale imaging and force probing of biomolecular systems using atomic force microscopy: From single molecules to living cells".Nanoscale 9.45(2017):17643-17666.