Genomic insights into the uncultured genus 'Candidatus Magnetobacterium' in the phylum Nitrospirae

doi:10.1038/ismej.2014.94

	Genomic insights into the uncultured genus 'Candidatus Magnetobacterium' in the phylum Nitrospirae
	Lin, Wei 1,2; Deng, Aihua 3; Wang, Zhang 4; Li, Ying 2,5,6; Wen, Tingyi 3; Wu, Long-Fei 2,7; Wu, Martin 4; Pan, Yongxin 1,2
刊名	ISME JOURNAL
	2014-12-01
卷号	8 期号:12 页码:2463-2477
ISSN号	1751-7362
DOI	10.1038/ismej.2014.94
文献子类	Article
英文摘要	Magnetotactic bacteria (MTB) of the genus 'Candidatus Magnetobacterium' in phylum Nitrospirae are of great interest because of the formation of hundreds of bullet-shaped magnetite magnetosomes in multiple bundles of chains per cell. These bacteria are worldwide distributed in aquatic environments and have important roles in the biogeochemical cycles of iron and sulfur. However, except for a few short genomic fragments, no genome data are available for this ecologically important genus, and little is known about their metabolic capacity owing to the lack of pure cultures. Here we report the first draft genome sequence of 3.42Mb from an uncultivated strain tentatively named 'Ca. Magnetobacterium casensis' isolated from Lake Miyun, China. The genome sequence indicates an autotrophic lifestyle using the Wood-Ljungdahl pathway for CO2 fixation, which has not been described in any previously known MTB or Nitrospirae organisms. Pathways involved in the denitrification, sulfur oxidation and sulfate reduction have been predicted, indicating its considerable capacity for adaptation to variable geochemical conditions and roles in local biogeochemical cycles. Moreover, we have identified a complete magnetosome gene island containing mam, mad and a set of novel genes (named as man genes) putatively responsible for the formation of bullet-shaped magnetite magnetosomes and the arrangement of multiple magnetosome chains. This first comprehensive genomic analysis sheds light on the physiology, ecology and biomineralization of the poorly understood 'Ca. Magnetobacterium' genus.
WOS关键词	MULTIPLE SEQUENCE ALIGNMENT ; NITRITE-OXIDIZING BACTERIA ; SULFATE-REDUCING BACTERIUM ; COCCUS STRAIN MC-1 ; MAGNETOTACTIC BACTERIA ; MAGNETOSOME FORMATION ; THERMODESULFOVIBRIO-YELLOWSTONII ; MAGNETOSPIRILLUM-GRYPHISWALDENSE ; SUBSYSTEMS TECHNOLOGY ; CHROMATIUM-VINOSUM
WOS研究方向	Environmental Sciences & Ecology ; Microbiology
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000345498200012
资助机构	CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; NSFC(41104041 ; NSFC(41104041 ; 41330104 ; 41330104 ; 31300065) ; 31300065) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; NSFC(41104041 ; NSFC(41104041 ; 41330104 ; 41330104 ; 31300065) ; 31300065) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; NSFC(41104041 ; NSFC(41104041 ; 41330104 ; 41330104 ; 31300065) ; 31300065) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; CAS/SAFEA International Partnership Program for Creative Research Teams(KZCX2-YW-T10) ; NSFC(41104041 ; NSFC(41104041 ; 41330104 ; 41330104 ; 31300065) ; 31300065)
内容类型	期刊论文
源URL	[http://ir.iggcas.ac.cn/handle/132A11/86650]
专题	中国科学院地质与地球物理研究所
通讯作者	Pan, Yongxin
作者单位	1.Chinese Acad Sci, Inst Geol & Geophys, Key Lab Earths Deep Interior, Paleomagnetism & Geochronol Lab,Biogeomagnetism G, Beijing 100029, Peoples R China 2.Chinese Acad Sci, France China Biomineralizat & Nanostruct Lab, Beijing 100029, Peoples R China 3.Chinese Acad Sci, Inst Microbiol, Key Lab Microbial Physiol & Metab Engn, Beijing 100029, Peoples R China 4.Univ Virginia, Dept Biol, Charlottesville, VA USA 5.China Agr Univ, Coll Biol Sci, State Key Lab Agrobiotechnol, Beijing 100094, Peoples R China 6.China Agr Univ, Coll Biol Sci, Lab Int Associe Franco Chinois Biomineralisat & N, Beijing 100094, Peoples R China 7.Aix Marseille Univ, CNRS, Chim Bacterienne Lab, Marseille 20, France
推荐引用方式 GB/T 7714	Lin, Wei,Deng, Aihua,Wang, Zhang,et al. Genomic insights into the uncultured genus 'Candidatus Magnetobacterium' in the phylum Nitrospirae[J]. ISME JOURNAL,2014,8(12):2463-2477.
APA	Lin, Wei.,Deng, Aihua.,Wang, Zhang.,Li, Ying.,Wen, Tingyi.,...&Pan, Yongxin.(2014).Genomic insights into the uncultured genus 'Candidatus Magnetobacterium' in the phylum Nitrospirae.ISME JOURNAL,8(12),2463-2477.
MLA	Lin, Wei,et al."Genomic insights into the uncultured genus 'Candidatus Magnetobacterium' in the phylum Nitrospirae".ISME JOURNAL 8.12(2014):2463-2477.