Taking the group of IT R&D personnel as the research subject, we investigated 267 employees through the questionnaire of work-family conflict, work-family promotion, psychological contract and turnover intention. The results showed: 1) Work-family conflict negatively affects psychological contract, and positively affects turnover intention; 2) Work-family promotion positively affects psychological contract, and negatively affects turnover intention; 3) Psychological contract partly mediates the effect of work-family conflict and promotion on turnover intention. This study filled the gaps of theoretical research, and provided realistic suggestions to the enterprise how to reduce turnover rate.