Olfactory identification deficit and its relationship with hedonic traits in patients with first-episode schizophrenia and individuals with schizotypy

doi:10.1016/j.pnpbp.2018.01.014

CORC > 心理研究所 > 中国科学院心理研究所 > 中国科学院心理健康重点实验室

	Olfactory identification deficit and its relationship with hedonic traits in patients with first-episode schizophrenia and individuals with schizotypy
	Zou, Lai-quan 1,2,3; Zhou, Han-yu 2,3; Lui, Simon S. Y.2,4; Wang, Yi2 ; Wang, Ya2 ; Gan, Jun 5,6; Zhu, Xiong-zhao 5,6; Cheung, Eric F. C.4; Chan, Raymond C. K.2,3 ; Raymond C.K. Chan
刊名	PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
	2018-04-20
卷号	83 期号:83 页码:137-141
关键词	Schizophrenia Social anhedonia Olfactory identification
ISSN号	0278-5846
DOI	10.1016/j.pnpbp.2018.01.014
产权排序	2
文献子类	Article
英文摘要	Objective Olfactory identification impairments have been consistently found in schizophrenia patients. However, few previous studies have investigated this in first-episode patients. There are also inconsistent findings regarding olfactory identification ability in psychometrically-defined schizotypy individuals. In this study, we directly compared the olfactory identification ability of first-episode schizophrenia patients with schizotypy individuals. The relationship between olfactory identification impairments and hedonic traits was also examined. Methods Thirty-five first-episode schizophrenia patients, 40 schizotypy individuals as defined by the Chapman's Anhedonia Scales and 40 demographically matched controls were recruited. The University of Pennsylvania Smell Identification Test was administered. Hedonic capacity was assessed using the Temporal Experience of Pleasure Scale (TEPS). Results The results showed that both the schizophrenia and schizotypy groups showed poorer olfactory identification ability than controls, and the impairment was significantly correlated with reduced pleasure experiences. Conclusion Our findings support olfactory identification impairment as a trait marker for schizophrenia. ; Objective: Olfactory identification impairments have been consistently found in schizophrenia patients. However, few previous studies have investigated this in first-episode patients. There are also inconsistent findings regarding olfactory identification ability in psychometrically-defined schizotypy individuals. In this study, we directly compared the olfactory identification ability of first-episode schizophrenia patients with schizotypy individuals. The relationship between olfactory identification impairments and hedonic traits was also examined.
WOS关键词	PSYCHOSIS ; PLEASURE ; SCALE ; EXPERIENCE ; ANHEDONIA ; SYMPTOMS ; SPECTRUM ; SAMPLE
WOS研究方向	Neurosciences & Neurology ; Pharmacology & Pharmacy ; Psychiatry
语种	英语
WOS记录号	WOS:000424703700016
资助机构	National Key Research and Development Programme(2016YFC0906402) ; National Natural Science Foundation of China(81571317 ; Beijing Municipal Science & Technology Commission(Z161100000216138) ; Beijing Training Project for the Leading Talents in Science and Technology(Z151100000315020) ; Natural Science Foundation of Guangdong Province, China(2017A030310069) ; 31700963)
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/25688]
专题	心理研究所_中国科学院心理健康重点实验室心理研究所_健康与遗传心理学研究室
通讯作者	Raymond C.K. Chan
作者单位	1.Southern Med Univ, Sch Publ Hlth, Dept Psychol, Guangdong Prov Key Lab Trop Dis Res, Guangzhou, Guangdong, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China 5.Cent S Univ, Xiangya Hosp 2, Med Psychol Ctr, Changsha, Hunan, Peoples R China 6.Cent S Univ, Med Psychol Inst, Changsha, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Zou, Lai-quan,Zhou, Han-yu,Lui, Simon S. Y.,et al. Olfactory identification deficit and its relationship with hedonic traits in patients with first-episode schizophrenia and individuals with schizotypy[J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,2018,83(83):137-141.
APA	Zou, Lai-quan.,Zhou, Han-yu.,Lui, Simon S. Y..,Wang, Yi.,Wang, Ya.,...&Raymond C.K. Chan.(2018).Olfactory identification deficit and its relationship with hedonic traits in patients with first-episode schizophrenia and individuals with schizotypy.PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,83(83),137-141.
MLA	Zou, Lai-quan,et al."Olfactory identification deficit and its relationship with hedonic traits in patients with first-episode schizophrenia and individuals with schizotypy".PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 83.83(2018):137-141.