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	Meta-analysis of prospective memory in schizophrenia: Nature, extent, and correlates
	Wang, Ya1,2; Cui, Jifang3; Chan, Raymond C. K.1,2; Deng, Yongyu4; Shi, Haisong5; Hong, Xiaohong6; Li, Zhanjiang7; Yu, Xin8; Gong, Qi-yong9; Shum, David10,11
刊名	SCHIZOPHRENIA RESEARCH
	2009-10-01
卷号	114期号:1-3页码:64-70
关键词	Schizophrenia Prospective memory Prefrontal lobe Meta-analysis
ISSN号	0920-9964
文献子类	Review
英文摘要	Prospective memory (PM) is the ability to remember to carry out an intended action in the future and it is an important function for everyday living. Studies have found that the neural basis of PM is located mainly in the prefrontal lobes (particularly in Brodmann Area 10) and patients with schizophrenia have functional deficits in this area. The present study provided a meta-analytic review of PM performances in patients with schizophrenia in 11 studies. A total of 485 patients with schizophrenia and 409 controls were included. Results showed that patients with schizophrenia exhibited impairments in all time- (d = -1.33), event- (d = -0.827). and activity-based (d = -0.729) PM, with time-based PM more impaired than event-based PM. In addition, PM was found to be significantly correlated with negative symptoms (r = -0.18), general psychopathology (r = -0.168), medication dosage (r = -0.119), duration of illness (r = -0.131), age (r = -0.23), education (r = 0.249), IQ (r = 0.439) and premorbid IQ (r = 0.356). It has theoretical and clinical implications. Theoretically, the results indicate time-based PM involves more initiation than event-based PM. Clinically, the results indicate patients on high dose of antipsychotic medication and with long duration of illness need special attention from care givers for PM problems.; Prospective memory (PM) is the ability to remember to carry out an intended action in the future and it is an important function for everyday living. Studies have found that the neural basis of PM is located mainly in the prefrontal lobes (particularly in Brodmann Area 10) and patients with schizophrenia have functional deficits in this area. The present study provided a meta-analytic review of PM performances in patients with schizophrenia in 11 studies. A total of 485 patients with schizophrenia and 409 controls were included. Results showed that patients with schizophrenia exhibited impairments in all time- (d = -1.33), event- (d = -0.827). and activity-based (d = -0.729) PM, with time-based PM more impaired than event-based PM. In addition, PM was found to be significantly correlated with negative symptoms (r = -0.18), general psychopathology (r = -0.168), medication dosage (r = -0.119), duration of illness (r = -0.131), age (r = -0.23), education (r = 0.249), IQ (r = 0.439) and premorbid IQ (r = 0.356). It has theoretical and clinical implications. Theoretically, the results indicate time-based PM involves more initiation than event-based PM. Clinically, the results indicate patients on high dose of antipsychotic medication and with long duration of illness need special attention from care givers for PM problems. (C) 2009 Elsevier B.V. All rights reserved.
学科主题	认知神经科学 ; 精神病学
语种	英语
WOS记录号	WOS:000270758700009
公开日期	2011-08-22
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/5540]
专题	心理研究所_中国科学院心理研究所回溯数据库(1956-2010)
通讯作者	Raymond C.K. Chan
作者单位	1.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 3.Beijing Normal Univ, Sch Psychol, Beijing 100875, Peoples R China 4.Zhongkai Univ Agr & Technol, Guangzhou, Guangdong, Peoples R China 5.N China Elect Power Univ, Beijing, Peoples R China 6.Shantou Univ, Mental Hlth Ctr, Shantou, Peoples R China 7.Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China 8.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China 9.Sichuan Univ, W China Sch Med, W China Hosp, Dept Radiol,Huaxi MR Res Ctr, Chengdu 610064, Peoples R China 10.Griffith Univ, Sch Psychol, Brisbane, Qld 4111, Australia
推荐引用方式 GB/T 7714	Wang, Ya,Cui, Jifang,Chan, Raymond C. K.,et al. Meta-analysis of prospective memory in schizophrenia: Nature, extent, and correlates[J]. SCHIZOPHRENIA RESEARCH,2009,114(1-3):64-70.
APA	Wang, Ya.,Cui, Jifang.,Chan, Raymond C. K..,Deng, Yongyu.,Shi, Haisong.,...&Raymond C.K. Chan.(2009).Meta-analysis of prospective memory in schizophrenia: Nature, extent, and correlates.SCHIZOPHRENIA RESEARCH,114(1-3),64-70.
MLA	Wang, Ya,et al."Meta-analysis of prospective memory in schizophrenia: Nature, extent, and correlates".SCHIZOPHRENIA RESEARCH 114.1-3(2009):64-70.

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