Synergy of glutathione, dithiothreitol and N-acetyl-L-cysteine self-assembled monolayers for electrochemical assay: sensitive determination of arsenic(III) in environmental and drinking water

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 山东省海岸带环境工程技术研究中心

	Synergy of glutathione, dithiothreitol and N-acetyl-L-cysteine self-assembled monolayers for electrochemical assay: sensitive determination of arsenic(III) in environmental and drinking water
	Chen, Lingxin1 ; Zhou, Na 1; Li, Jinhua1 ; Chen, Zhaopeng1 ; Liao, Chunyang1 ; Chen, Jiannong 2
刊名	ANALYST
	2011
卷号	136 期号:21 页码:4526-4532
关键词	Atomic Fluorescence Spectrometry Anodic-stripping Voltammetry Modified Gold Electrode Dna Hybridization Carbon Electrode Acid Speciation Oxidation Preconcentration Identification
ISSN号	0003-2654
通讯作者	Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China
产权排序	[Chen, Lingxin; Zhou, Na; Li, Jinhua; Chen, Zhaopeng; Liao, Chunyang] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Chen, Jiannong] Ludong Univ, Dept Phys, Yantai 264025, Peoples R China
文献子类	Article
英文摘要	A simple and efficient electrochemical assay based on self-assembled monolayers (SAMs) was developed for the highly sensitive determination of arsenic(III) in water samples. The synergy of glutathione (GSH), dithiothreitol (DTT) and N-acetyl-L-cysteine (NAC) mixed SAMs enhanced the detection specificity and sensitivity of As(III) in water samples, resulting from the immobilization of a large number of As(III) moieties on the gold electrode surface via As-O and As-S linkages. After accumulating As(III), anodic stripping voltammetry (ASV) was performed, and linear sweep voltammetry (LSV) was employed for signal recording. Several main voltammetric parameters were optimized as follows: supporting electrolyte, 1 mol L(-1) HCl; deposition potential, -0.35 V; deposition time, 150 s. A good linear relationship (R - 0.9980) was attained between the concentration of the As(III) standard and peak current, in the range of 3-100 mu g L(-1). The limit of detection (LOD) of this sensing system was determined to be 0.5 mu g L(-1) at a signal-to-noise ratio of 3. A variety of common coexistent ions in water samples were examined, showing no obvious interferences on the As(III) determination. The amenability of this method to the analyses of water samples was also investigated. High recovery of 90.5% with the precision of 5.1% at spiked 10 mu g L(-1), and low LOD of 0.3 mu g L(-1) were obtained in seawater. The synergy effect of GSH, DTT and NAC provided the possibility for the rapid and sensitive LSV determination of As(III) in complicated water samples.; A simple and efficient electrochemical assay based on self-assembled monolayers (SAMs) was developed for the highly sensitive determination of arsenic(III) in water samples. The synergy of glutathione (GSH), dithiothreitol (DTT) and N-acetyl-L-cysteine (NAC) mixed SAMs enhanced the detection specificity and sensitivity of As(III) in water samples, resulting from the immobilization of a large number of As(III) moieties on the gold electrode surface via As-O and As-S linkages. After accumulating As(III), anodic stripping voltammetry (ASV) was performed, and linear sweep voltammetry (LSV) was employed for signal recording. Several main voltammetric parameters were optimized as follows: supporting electrolyte, 1 mol L(-1) HCl; deposition potential, -0.35 V; deposition time, 150 s. A good linear relationship (R - 0.9980) was attained between the concentration of the As(III) standard and peak current, in the range of 3-100 mu g L(-1). The limit of detection (LOD) of this sensing system was determined to be 0.5 mu g L(-1) at a signal-to-noise ratio of 3. A variety of common coexistent ions in water samples were examined, showing no obvious interferences on the As(III) determination. The amenability of this method to the analyses of water samples was also investigated. High recovery of 90.5% with the precision of 5.1% at spiked 10 mu g L(-1), and low LOD of 0.3 mu g L(-1) were obtained in seawater. The synergy effect of GSH, DTT and NAC provided the possibility for the rapid and sensitive LSV determination of As(III) in complicated water samples.
学科主题	Chemistry
URL标识	查看原文
WOS关键词	ATOMIC FLUORESCENCE SPECTROMETRY ; ANODIC-STRIPPING VOLTAMMETRY ; MODIFIED GOLD ELECTRODE ; DNA HYBRIDIZATION ; CARBON ELECTRODE ; ACID ; SPECIATION ; OXIDATION ; PRECONCENTRATION ; IDENTIFICATION
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000295727900022
资助机构	National Natural Science Foundation of China[20975089, 20907039]; Chinese Academy of Sciences[KZCX2-EW-206]; Department of Science and Technology of Shandong Province of China[2008GG20005005]; Yantai Research and Development Program of China[2010158, 2007323]; Natural Science Foundation of Shandong Province of China[ZR2010BQ027]; Shandong province scientific instrument equipment upgrading technology project[2010GJC20808-16]
公开日期	2012-03-06
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/5345]
专题	烟台海岸带研究所_山东省海岸带环境工程技术研究中心烟台海岸带研究所_污染过程与控制实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China 2.Ludong Univ, Dept Phys, Yantai 264025, Peoples R China
推荐引用方式 GB/T 7714	Chen, Lingxin,Zhou, Na,Li, Jinhua,et al. Synergy of glutathione, dithiothreitol and N-acetyl-L-cysteine self-assembled monolayers for electrochemical assay: sensitive determination of arsenic(III) in environmental and drinking water[J]. ANALYST,2011,136(21):4526-4532.
APA	Chen, Lingxin,Zhou, Na,Li, Jinhua,Chen, Zhaopeng,Liao, Chunyang,&Chen, Jiannong.(2011).Synergy of glutathione, dithiothreitol and N-acetyl-L-cysteine self-assembled monolayers for electrochemical assay: sensitive determination of arsenic(III) in environmental and drinking water.ANALYST,136(21),4526-4532.
MLA	Chen, Lingxin,et al."Synergy of glutathione, dithiothreitol and N-acetyl-L-cysteine self-assembled monolayers for electrochemical assay: sensitive determination of arsenic(III) in environmental and drinking water".ANALYST 136.21(2011):4526-4532.