Synthesis, characterization, and antifungal activity of novel quaternary chitosan derivatives

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	Synthesis, characterization, and antifungal activity of novel quaternary chitosan derivatives
	Li, Rongchun 2,3; Guo, Zhanyong1 ; Jiang, Pingan 3
刊名	CARBOHYDRATE RESEARCH
	2010-09-03
卷号	345 期号:13 页码:1896-1900
关键词	Quaternary Chitosan Chloracetyl Chitosan 5-chlorosalicylaldehyde 5-bromosalicylaldehyde Antifungal Activity
ISSN号	0008-6215
通讯作者	Guo, ZY, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
产权排序	[Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Li, Rongchun] Dezhou Univ, Dept Chem, Dezhou 253023, Peoples R China; [Li, Rongchun; Jiang, Pingan] Xinjiang Agr Univ, Coll Pratacultural & Environm Sci, Urumqi 830052, Peoples R China
文献子类	Article
英文摘要	Three novel quaternary chitosan derivatives were successfully synthesized by reaction of chloracetyl chitosan (CACS) with pyridine (PACS), 4-(5-chloro-2-hydroxybenzylideneamino)-pyridine (CHPACS), and 4-(5-bromo-2-hydroxybenzylideneamino)-pyridine (BHPACS). The chemical structure of the prepared chitosan derivatives was confirmed by Fourier transform infrared (FT-IR) and C-13 nuclear magnetic resonance (C-13 NMR) and their antifungal activity against Cladosporium cucumerinum, Monilinia fructicola, Colletotrichum lagenarium, and Fusarium oxysporum was assessed. Comparing with the antifungal activity of chitosan, CACS, and PACS, CHPACS and BHPACS exhibited obviously better inhibitory effects, which should be related to the synergistic reaction of chitosan itself with the grafted 2-[4-(5-chloro-2-hydroxybenzylideneamino)-pyridyl]acetyl and 2[4-(5-bromo-2-hydroxybenzylideneamino)-pyridyl]acetyl. (C) 2010 Elsevier Ltd. All rights reserved.; Three novel quaternary chitosan derivatives were successfully synthesized by reaction of chloracetyl chitosan (CACS) with pyridine (PACS), 4-(5-chloro-2-hydroxybenzylideneamino)-pyridine (CHPACS), and 4-(5-bromo-2-hydroxybenzylideneamino)-pyridine (BHPACS). The chemical structure of the prepared chitosan derivatives was confirmed by Fourier transform infrared (FT-IR) and (13)C nuclear magnetic resonance ((13)C NMR) and their antifungal activity against Cladosporium cucumerinum, Monilinia fructicola, Colletotrichum lagenarium, and Fusarium oxysporum was assessed. Comparing with the antifungal activity of chitosan, CACS, and PACS, CHPACS and BHPACS exhibited obviously better inhibitory effects, which should be related to the synergistic reaction of chitosan itself with the grafted 2-[4-(5-chloro-2-hydroxybenzylideneamino)-pyridyl]acetyl and 2[4-(5-bromo-2-hydroxybenzylideneamino)-pyridyl]acetyl. (C) 2010 Elsevier Ltd. All rights reserved.
学科主题	Biochemistry & Molecular Biology ; Chemistry, Applied ; Chemistry, Organic
URL标识	查看原文
WOS关键词	ANTIMICROBIAL ACTIVITY ; IN-VITRO ; FUNGI ; SPECTRA ; SCHIFF ; GROWTH ; CHITIN ; AGENT ; BASES ; ACID
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:000281998300012
资助机构	Chinese Academy of Sciences [kzcx2-yw-225]
公开日期	2011-07-14
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/3774]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Dezhou Univ, Dept Chem, Dezhou 253023, Peoples R China 3.Xinjiang Agr Univ, Coll Pratacultural & Environm Sci, Urumqi 830052, Peoples R China
推荐引用方式 GB/T 7714	Li, Rongchun,Guo, Zhanyong,Jiang, Pingan. Synthesis, characterization, and antifungal activity of novel quaternary chitosan derivatives[J]. CARBOHYDRATE RESEARCH,2010,345(13):1896-1900.
APA	Li, Rongchun,Guo, Zhanyong,&Jiang, Pingan.(2010).Synthesis, characterization, and antifungal activity of novel quaternary chitosan derivatives.CARBOHYDRATE RESEARCH,345(13),1896-1900.
MLA	Li, Rongchun,et al."Synthesis, characterization, and antifungal activity of novel quaternary chitosan derivatives".CARBOHYDRATE RESEARCH 345.13(2010):1896-1900.