Sesteralterin and Tricycloalterfurenes A-D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1

doi:10.1021/acs.jnatprod.7b00478

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	Sesteralterin and Tricycloalterfurenes A-D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1
	Shi, Zhen-Zhen 1,2; Miao, Feng-Ping1 ; Fang, Sheng-Tao1 ; Liu, Xiang-Hong 1; Yin, Xiu-Li1 ; Ji, Nai-Yun1 ; Ji, Nai-Yun(Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China)
刊名	JOURNAL OF NATURAL PRODUCTS
	2017-09-01
卷号	80 期号:9 页码:2524-2529
ISSN号	0163-3864
DOI	10.1021/acs.jnatprod.7b00478
产权排序	第1完成单位
文献子类	Article
英文摘要	A new sesterterpene; sesteralterin (1), four new meroterpenes, tricycloalterfurenes A-D (2-5), and a known meroterpene, TCA-F (6), were obtained from the culture extract of an Alternaria alternate strain (k21-1) isolated from the surface of the marine red alga Lomentaria hakodatensis. The structures and relative/absolute configurations of these compounds were identified by spectroscopic analyses, mainly including 1D/2D NMR, ECD, and mass spectra and quantum chemical calculations. Compound 1 represents the first nitidasane sesterterpene naturally produced by fungi, and 2-5 feature a tetrahydrofuran unit rarely occurring in tricycloalternarenes. Compounds 1-6 were assayed for inhibition of the growth of four marine plankton and one marine alga-pathogenic bacterium.
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WOS关键词	ALGICOLOUS STRAIN ; TRICYCLOALTERNARENES ; DERIVATIVES ; MEROTERPENOIDS ; TOXINS
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000411848300018
资助机构	Open Fund of Key Laboratory of Experimental Marine Biology, Chinese Academy of Sciences(KF2017NO4) ; Key Cutting-Edge Research Program of the Chinese Academy of Sciences(QYZDB-SSW-DQC013) ; National Natural Science Foundation of China(31670355) ; Natural Science Foundation for Distinguished Young Scholars of Shandong Province(JQ201712) ; Yantai Municipal Sci-Tech Development Program(2015ZH076)
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/23450]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
通讯作者	Ji, Nai-Yun; Ji, Nai-Yun(Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China)
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Shi, Zhen-Zhen,Miao, Feng-Ping,Fang, Sheng-Tao,et al. Sesteralterin and Tricycloalterfurenes A-D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1[J]. JOURNAL OF NATURAL PRODUCTS,2017,80(9):2524-2529.
APA	Shi, Zhen-Zhen.,Miao, Feng-Ping.,Fang, Sheng-Tao.,Liu, Xiang-Hong.,Yin, Xiu-Li.,...&Ji, Nai-Yun.(2017).Sesteralterin and Tricycloalterfurenes A-D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1.JOURNAL OF NATURAL PRODUCTS,80(9),2524-2529.
MLA	Shi, Zhen-Zhen,et al."Sesteralterin and Tricycloalterfurenes A-D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1".JOURNAL OF NATURAL PRODUCTS 80.9(2017):2524-2529.