Separation behavior of basic compounds on unbonded silicon oxynitride and silica high-performance liquid chromatography stationary phases with reversed-phase eluents

	Separation behavior of basic compounds on unbonded silicon oxynitride and silica high-performance liquid chromatography stationary phases with reversed-phase eluents
	Xue, Xingya 2; Liang, Xinmiao 2; Wan, Huihui 1; Zhong, Hongmin 1
刊名	JOURNAL OF SEPARATION SCIENCE
	2016-10-01
卷号	39 期号:20 页码:3860-3867
关键词	Basic compounds Hydrophobicity Reversed-phase eluents Silica Silicon oxynitride
英文摘要	Unbonded silicon oxynitride and silica high-performance liquid chromatography stationary phases have been evaluated and compared for the separation of basic compounds of differing molecular weight, pKa, and log D using aqueous/organic mobile phases. The influences of percentage of organic modifier, buffer pH, and concentration in the mobile phase on base retention were investigated on unbonded silicon oxynitride and silica phases. The results confirmed that unbonded silicon oxynitride and silica phases demonstrated excellent separation performance for model basic compounds and both the unbonded phases examined possessed a hydrophobic/adsorption and ion-exchange character. The silicon oxynitride stationary phase exhibited high hydrophilicity compared with silica with a reversed-phase mobile phase. An ion-exclusion-type mechanism becomes predominant for the separation of three aimed bases on the silicon oxynitride column at pH 2.8. Different from silicon oxynitride stationary phase, no obvious change for the retention time of three model bases on silica stationary phase at pH 2.8 can be observed.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Analytical
关键词[WOS]	RETENTION ; COLUMNS ; SOLUTES ; HPLC ; NITRIDATION ; OVERLOAD ; MCM-41 ; MODEL
收录类别	SCI
语种	英语
WOS记录号	WOS:000389045100002
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/150416]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Dalian Univ Technol, Fac Chem Environm & Biol Sci & Technol, Analyt Ctr, Dalian 116024, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China
推荐引用方式 GB/T 7714	Xue, Xingya,Liang, Xinmiao,Wan, Huihui,et al. Separation behavior of basic compounds on unbonded silicon oxynitride and silica high-performance liquid chromatography stationary phases with reversed-phase eluents[J]. JOURNAL OF SEPARATION SCIENCE,2016,39(20):3860-3867.
APA	Xue, Xingya,Liang, Xinmiao,Wan, Huihui,&Zhong, Hongmin.(2016).Separation behavior of basic compounds on unbonded silicon oxynitride and silica high-performance liquid chromatography stationary phases with reversed-phase eluents.JOURNAL OF SEPARATION SCIENCE,39(20),3860-3867.
MLA	Xue, Xingya,et al."Separation behavior of basic compounds on unbonded silicon oxynitride and silica high-performance liquid chromatography stationary phases with reversed-phase eluents".JOURNAL OF SEPARATION SCIENCE 39.20(2016):3860-3867.