N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry

	N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry
	Ge, Guangbo 1; Cheng, Xina 1; Ye, Xueting 2; Liu, Dan 1; Zhao, Nan 1; Gao, Huiyuan 2; Wang, Ping 1; Zhang, Xiaozhe 1
刊名	RAPID COMMUNICATIONS IN MASS SPECTROMETRY
	2017-11-15
卷号	31 期号:21 页码:1779-1784
英文摘要	Rationale: The matrix plays an essential role in defining detection limits and ionization yields of analytes in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis. Small molecule MALDI-MS analyses commonly suffer from the high background interference generated from matrices. Moreover, the inhomogeneous crystallization of some matrices, such as 2,5-dihydroxybenzoic acid (DHB), is to the detriment of the quality or repeatability of detection. We have found that N-butyl-4-hydroxy-1,8-naphthalimide (BHN) can provide improved performance as a matrix for small molecule analysis.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
类目[WOS]	Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy
关键词[WOS]	MALDI-TOF MS ; DESORPTION IONIZATION ; PROTEINS ; METABOLITES
收录类别	SCI
语种	英语
WOS记录号	WOS:000412454500001
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/150076]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China 2.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Ge, Guangbo,Cheng, Xina,Ye, Xueting,et al. N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2017,31(21):1779-1784.
APA	Ge, Guangbo.,Cheng, Xina.,Ye, Xueting.,Liu, Dan.,Zhao, Nan.,...&Zhang, Xiaozhe.(2017).N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,31(21),1779-1784.
MLA	Ge, Guangbo,et al."N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 31.21(2017):1779-1784.