Experimental Study of Bone Marrow Stem Cell Inducing Osteogenesis on SLA Titanium Mesh Surface

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	Experimental Study of Bone Marrow Stem Cell Inducing Osteogenesis on SLA Titanium Mesh Surface
	Shi, L; Yang, L; Liu, RM; Tao, F; Liu, QR; Shi, L (reprint author), Gansu Prov Hosp, Oral Med Ctr, Lanzhou, Gansu, Peoples R China.
	2016
会议日期	JUL 15-17, 2016
会议地点	Shanghai, PEOPLES R CHINA
页码	391-398
英文摘要	Objective: Through animal experiments to understand medical titanium mesh in the sandblasting acid corrosion (SLA) before and after processing and surface coverage of BMSCs cell membrane after the effect of inducing osteogenesis, for medical titanium net covering the bone marrow stem cells after surface modification diaphragm local defect reconstruction of maxilla and form a bionic bone. Materials and methods: To observe the SLA titanium mesh surface morphology changes before and after processing; Making experimental rabbit BMSCs and culture cell cell membrane, According to the experimental steps and grouping plan will surface treatment before and after the experiment rabbit implanted with titanium mesh and cell membrane, after six months after feeding titanium mesh and the surface osteogenesis effect was observed and compared. Results: 1) Will be without surface treatment and after surface treatment of medical experimental rabbit implanted with titanium mesh directly, after take out the titanium mesh specimen observation, without surface treatment of the surface of the titanium mesh individual islands area is bone tissue osteogenesis effect is poorer, after surface treatment of titanium mesh is formed relatively complete bone tissue layer, but relatively weak bone tissue layer. 2) To the blanket in the diaphragm of BMSCs cells in medical titanium implant experimental animals, after take out the titanium mesh specimen observation, uncovered the cell membrane of titanium net, no matter whether it is for surface treatment, the surface osteogenesis effect are also covered the cell membrane of titanium mesh is poor. Conclusion: Bone marrow stem cell patch plays a decisive role in the process of titanium mesh inducing osteogenesis. Titanium mesh surface SLA processing only plays an auxiliary role. Therefore, the order from the best to the worst final effect of inducing osteogenesis is shown as follows: SLA processing + cell patch > no SLA processing + cell patch > SLA processing > no SLA processing.
会议录	PROCEEDINGS OF THE 2016 INTERNATIONAL CONFERENCE ON BIOMEDICAL AND BIOLOGICAL ENGINEERING
会议录出版地	PARIS
学科主题	Engineering ; Research & Experimental Medicine
语种	英语
WOS记录号	WOS:000390918200060
内容类型	会议论文
源URL	[http://ir.lzu.edu.cn/handle/262010/189721]
专题	学院待认领_会议论文
通讯作者	Shi, L (reprint author), Gansu Prov Hosp, Oral Med Ctr, Lanzhou, Gansu, Peoples R China.
推荐引用方式 GB/T 7714	Shi, L,Yang, L,Liu, RM,et al. Experimental Study of Bone Marrow Stem Cell Inducing Osteogenesis on SLA Titanium Mesh Surface[C]. 见:. Shanghai, PEOPLES R CHINA. JUL 15-17, 2016.