Clinical characteristics of Henoch-Schonlein purpura in children

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	Clinical characteristics of Henoch-Schonlein purpura in children
	Liu, Li-Jun; Yu, Jing; Li, Yu-Ning
刊名	中国当代儿科杂志
	2015-10
卷号	17 期号:10 页码:1079-1083
关键词	过敏性紫癜紫癜性肾炎回顾性分析儿童
ISSN号	1008-8830
其他题名	儿童过敏性紫癜325例回顾性分析
文献子类	Article
英文摘要	OBJECTIVE: To explore the clinical characteristics of Henoch-Schonlein purpura (HSP) in children.METHODS: The clinical data of 325 hospitalized children who were diagnosed with HSP between June 2012 and June 2014 were analyzed retrospectively.RESULTS: In the 325 children with HSP, the incidence of HSP was higher in winter and spring, with 33.9% and 27.4%, respectively. Infection was the major factor to induce HSP (57.2%). The incidence of renal damage in children with purpura accompanied by abdominal symptoms and children with purpura accompanied by abdominal and joint symptoms was 60.3% and 48.9%, respectively, with statistically significant differences compared with children with purpura alone (P<0.05). In 32 children with purpura nephritis, the pathological grades of IIIa and IIIb were more common, accounting for 28% and 31%, respectively. In 325 children, an increased serum D-dimer level was observed in 260 children (80.0%), an increased peripheral IgA content in 101 children (46.3%), and a decreased CD4+ cell percentage in 62 children (56.4%).CONCLUSIONS: A high incidence of HSP is often seen in spring and winter. HSP is often induced by upper respiratory tract infection. Renal damage is more likely to occur in children with digestive tract symptoms, with IIIa and IIIb as the common pathological grades of renal damage.
学科主题	Pediatrics ; Demography ; Urology & Nephrology ; Hematology ; Environmental Sciences & Ecology (Provided By Thomson Reuters)
出版地	CHANGSHA
语种	中文
CSCD记录号	CSCD:5550945
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/178599]
专题	第一临床医学院_期刊论文
推荐引用方式 GB/T 7714	Liu, Li-Jun,Yu, Jing,Li, Yu-Ning. Clinical characteristics of Henoch-Schonlein purpura in children[J]. 中国当代儿科杂志,2015,17(10):1079-1083.
APA	Liu, Li-Jun,Yu, Jing,&Li, Yu-Ning.(2015).Clinical characteristics of Henoch-Schonlein purpura in children.中国当代儿科杂志,17(10),1079-1083.
MLA	Liu, Li-Jun,et al."Clinical characteristics of Henoch-Schonlein purpura in children".中国当代儿科杂志 17.10(2015):1079-1083.