Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment

doi:10.2147/NDT.S102929

CORC > 兰州大学 > 兰州大学 > 第一临床医学院 > 期刊论文

	Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment
	Sun, HT; Zheng, MH; Wang, YM; Diao, YF; Zhao, WY; Wei, ZJ; Sun, HT (reprint author), Univ Peoples Armed Police Force, Affiliated Hosp Logist, Sixth Dept Neurosurg, 220 Chenglin Rd, Tianjin 300162, Peoples R China.
刊名	NEUROPSYCHIATRIC DISEASE AND TREATMENT
	2016
卷号	12 页码:2125-2129
关键词	severe traumatic brain injury hypothermia brain tissue partial pressure of oxygen therapy
ISSN号	1178-2021
DOI	10.2147/NDT.S102929
文献子类	Article
英文摘要	Objective: The aim of this study was to investigate the clinical significance and changes of brain tissue partial pressure of oxygen (PbtO2) in the course of mild hypothermia treatment (MHT) for treating severe traumatic brain injury (sTBI). Methods: There were 68 cases with sTBI undergoing MHT. PbtO2, intracranial pressure (ICP), jugular venous oxygen saturation (SjvO2), and cerebral perfusion pressure (CPP) were continuously monitored, and clinical outcomes were evaluated using the Glasgow Outcome Scale score. Results: Of 68 patients with sTBI, PbtO2, SjvO2, and CPP were obviously increased, but decreased ICP level was observed throughout the MHT. PbtO2 and ICP were negatively linearly correlated, while there was a positive linear correlation between PbtO2 and SjvO2. Monitoring CPP and SjvO2 was performed under normal circumstances, and a large proportion of patients were detected with low PbtO2. Decreased PbtO2 was also found after MHT. Conclusion: Continuous PbtO2 monitoring could be introduced to evaluate the condition of regional cerebral oxygen metabolism, thereby guiding the clinical treatment and predicting the outcome.
学科主题	Neurosciences & Neurology ; Psychiatry
出版地	ALBANY
资助项目	国家自然科学基金项目
项目编号	National Natural Science Foundation of China [814712751004949]
语种	英语
WOS记录号	WOS:000382209700004
资助机构	NSFC
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/178538]
专题	第一临床医学院_期刊论文
通讯作者	Sun, HT (reprint author), Univ Peoples Armed Police Force, Affiliated Hosp Logist, Sixth Dept Neurosurg, 220 Chenglin Rd, Tianjin 300162, Peoples R China.
推荐引用方式 GB/T 7714	Sun, HT,Zheng, MH,Wang, YM,et al. Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment[J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT,2016,12:2125-2129.
APA	Sun, HT.,Zheng, MH.,Wang, YM.,Diao, YF.,Zhao, WY.,...&Sun, HT .(2016).Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment.NEUROPSYCHIATRIC DISEASE AND TREATMENT,12,2125-2129.
MLA	Sun, HT,et al."Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment".NEUROPSYCHIATRIC DISEASE AND TREATMENT 12(2016):2125-2129.