Research on the performance of PGS/PLLA electrostatic spinning of composite nanofiber scaffold

doi:10.11896/j.issn.1005-023X.2016.14.015

CORC > 兰州大学 > 兰州大学 > 口腔医学院 > 期刊论文

	Research on the performance of PGS/PLLA electrostatic spinning of composite nanofiber scaffold
	Bao, Guangjie; Zhong, Ni; Zhang, Wenxia; Li, Yanmei; Lu, Wei; Zhang, Shujiang; Kang, Hong; Kang, Hong (kanghong@lzu.edu.cn)
刊名	材料导报
	2016-07-25
卷号	30 期号:7 页码:67-71 and 97
关键词	PGS PLLA 静电纺丝三维纳米支架
ISSN号	1005-023X
DOI	10.11896/j.issn.1005-023X.2016.14.015
其他题名	PGS/PLLA静电纺丝复合纳米纤维支架的性能研究
文献子类	Article
英文摘要	A novel electrospinning scaffold material of poly glycerol-sebacate/poly-L-lactic acid (PGS/PLLA) was prepared. The 25% spinning solutions were prepared with mass ratios of PGS and PLLA of 1:3, 1:1 and 3:1 respectively, taking hexafluoroisopropanol (HFIP) as the solvent. Scaffold material was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction(XRD), thermogravimetry (TG), Instron testing machine, and water contact angle (WCA) analysis. SEM observation showed that the electrospinning material had uniform, interwoven network structure. FT-IR and XRD analysis indicated that the addition of PLLA had little impact on the structure of PGS polymer and the crystallinity of scaffold material increased with the increasing of PGS level. TG reported that PLLA increased thermal stability of the PGS/PLLA co-electrospun material. WCA analysis indicated good hydrophilic property and the tensile testing showed excellent mechanical pro-perty. Biological experiment under co-cultured goat temporomandibular joint disc cells with PGS/PLLA scaffold indicated that the cells presented a favorable adhesion and proliferation on the optimized three dimensional PGS/PLLA(1/3 group) scaffold. © 2016, Materials Review Magazine. All right reserved.
学科主题	Biomedical Engineering ; Thermodynamics ; Nanotechnology ; Chemistry ; Organic Compounds
出版地	CHONGQING
资助项目	国家自然科学基金项目
项目编号	国家自然科学基金
语种	中文
CSCD记录号	CSCD:5792846
资助机构	NSFC
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179504]
专题	口腔医学院_期刊论文
通讯作者	Kang, Hong (kanghong@lzu.edu.cn)
推荐引用方式 GB/T 7714	Bao, Guangjie,Zhong, Ni,Zhang, Wenxia,et al. Research on the performance of PGS/PLLA electrostatic spinning of composite nanofiber scaffold[J]. 材料导报,2016,30(7):67-71 and 97.
APA	Bao, Guangjie.,Zhong, Ni.,Zhang, Wenxia.,Li, Yanmei.,Lu, Wei.,...&Kang, Hong .(2016).Research on the performance of PGS/PLLA electrostatic spinning of composite nanofiber scaffold.材料导报,30(7),67-71 and 97.
MLA	Bao, Guangjie,et al."Research on the performance of PGS/PLLA electrostatic spinning of composite nanofiber scaffold".材料导报 30.7(2016):67-71 and 97.