Metal Exposure and Risk of Diabetes and Prediabetes among Chinese Occupational Workers

doi:10.3967/bes2015.121

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	Metal Exposure and Risk of Diabetes and Prediabetes among Chinese Occupational Workers
	Yang, AM; Cheng, N; Pu, HQ; Liu, SM; Li, JS; Bassig, BA; Dai, M; Li, HY; Hu, XB; Ren, XW
刊名	BIOMEDICAL AND ENVIRONMENTAL SCIENCES
	2015-12
卷号	28 期号:12 页码:875-883
关键词	Metals Occupational exposure Diabetes Prediabetes Risk factors
ISSN号	0895-3988
DOI	10.3967/bes2015.121
文献子类	Article
英文摘要	Objective To study the association between metal exposure and risk of diabetes and prediabetes among Chinese workers exposed to metals. Methods We used data obtained from the baseline survey of the Jinchang Cohort Study of workers in Jinchang Industry, the largest nickel production company in China. A total of 42,122 workers >= 20 years of age were included in the study. A standardized, structured questionnaire was used to collect epidemiological information. Physical examinations and laboratory tests were conducted to evaluate the health status of the participants and to measure various biomarkers including blood sugar, lipids, and urinary metal concentrations. Logistic regression was used to study the association between occupational groups categorized according to the measured metal levels (office workers, low-level; mining/production workers, mid-level; and smelting/refining workers, high-level) and risk of diabetes and prediabetes. Results The overall prevalence of diabetes and prediabetes was 7.5% and 16.8%, respectively. The adjusted odds ratios for diabetes among mining/production workers and smelting/refining workers compared to office workers were 1.5 (95% CI: 1.3, 1.7) and 3.8 (95% CI: 3.4, 4.3), respectively. No association was observed between these occupational groups and prediabetes in this study. Conclusion Occupations associated with higher levels of metal exposure were associated with an increased risk of diabetes in this cohort. More studies are needed to confirm this observed association.
学科主题	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
出版地	BEIJING
项目编号	Jinchuan Nonferrous Metals Corporation [JKB20120013] ; Fogarty training grants from the US National Institutes of Health [D43TW 008323, D43TW 007864-01]
语种	英语
CSCD记录号	CSCD:5621614
WOS记录号	WOS:000369158600003
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179622]
专题	公共卫生学院_期刊论文
通讯作者	Bai, YN (reprint author), Lanzhou Univ, Sch Publ Hlth, Inst Epidemiol & Stat, Lanzhou 730000, Gansu, Peoples R China.
推荐引用方式 GB/T 7714	Yang, AM,Cheng, N,Pu, HQ,et al. Metal Exposure and Risk of Diabetes and Prediabetes among Chinese Occupational Workers[J]. BIOMEDICAL AND ENVIRONMENTAL SCIENCES,2015,28(12):875-883.
APA	Yang, AM.,Cheng, N.,Pu, HQ.,Liu, SM.,Li, JS.,...&Bai, YN .(2015).Metal Exposure and Risk of Diabetes and Prediabetes among Chinese Occupational Workers.BIOMEDICAL AND ENVIRONMENTAL SCIENCES,28(12),875-883.
MLA	Yang, AM,et al."Metal Exposure and Risk of Diabetes and Prediabetes among Chinese Occupational Workers".BIOMEDICAL AND ENVIRONMENTAL SCIENCES 28.12(2015):875-883.