The Ameliorate Effect of Endomorphin 1 on the Mice Nephrotoxicity Induced by Cadmium

doi:10.1016/j.proenv.2011.10.097

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	The Ameliorate Effect of Endomorphin 1 on the Mice Nephrotoxicity Induced by Cadmium
	Gong, P; Chen, FX; Wang, R; Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
	2011
会议日期	NOV 25-27, 2011
会议地点	Male, MALDIVES
关键词	Cadmium Endomorphin 1 Kidney Oxidative Stress Antioxidant
卷号	8
DOI	10.1016/j.proenv.2011.10.097
页码	629-632
英文摘要	To wonder whether endomorphin 1(EM1), the antioxidative peptide, can protect against the renal toxicology of cadmium (Cd), which probably related to the oxidative injury. Methods: In vivo assays have been designed and performed, such as the measurement of oxidative damage parameters and the index of antioxidative system. Result: Data from our study demonstrated the effect of EM1 could ameliorate the increased concentration of lipid peroxidation products and protein carboxylatio and increase the content of antioxidative system, the antioxidant capacity of EM1 probably relate to its structure. Conclusion: Our study first demonstrated the nephrotoxicity induced by Cd can be suppressed by the treatment of EM1. (C) 2011 Published by Elsevier Ltd. Selection and/or peer-review under responsibility of the Asia-Pacific Chemical, Biological & Environmental Engineering Society (APCBEES)
会议录	2011 INTERNATIONAL CONFERENCE ON ENVIRONMENT SCIENCE AND BIOTECHNOLOGY (ICESB 2011)
会议录出版地	AMSTERDAM
学科主题	Biotechnology & Applied Microbiology ; Environmental Sciences & Ecology
语种	英语
ISSN号	1878-0296
WOS记录号	WOS:000312366100095
内容类型	会议论文
源URL	[http://ir.lzu.edu.cn/handle/262010/183010]
专题	基础医学院_会议论文
通讯作者	Wang, R (reprint author), Lanzhou Univ, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Gong, P,Chen, FX,Wang, R,et al. The Ameliorate Effect of Endomorphin 1 on the Mice Nephrotoxicity Induced by Cadmium[C]. 见:. Male, MALDIVES. NOV 25-27, 2011.