Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes

doi:10.1021/acs.orglett.5b01799

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	Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes
	Zhu, YY; Li, XY; Chen, Q; Su, JH; Jia, FJ; Qiu, S; Ma, MX; Sun, QT; Yan, WJ; Wang, KR
刊名	ORGANIC LETTERS
	2015-08-07
卷号	17 期号:15 页码:3826-3829
ISSN号	1523-7060
DOI	10.1021/acs.orglett.5b01799
文献子类	Article
英文摘要	A catalytic asymmetric method for the synthesis of 2-CF3 chromanes has been described. Generally, the squaramide-catalyzed cascade reaction of 2-hydroxychalcones with beta-CF3-nitroalkenes gave the CF3-containing heterocyclic compounds bearing three contiguous stereogenic centers in excellent yields, diastereoselectivities, and enantioselectivities.
学科主题	Chemistry
出版地	WASHINGTON
资助项目	国家自然科学基金项目 ; 国家科技重大专项 ; 高等学校博士学科点专项科研基金 ; 中央高校基本科研业务费专项资金
项目编号	National Natural Science Foundation of China [21432003, 21272108, 31200584, 91213302] ; Fundamental Research Funds for the Central Universities [lzujbky-2015-155] ; Research Fund for the Doctoral Program of Higher Education of China [20120211120045] ; Key National S&T Program "Major New Drug Development" of the Ministry of Science and Technology of China [2012ZX09504001-003]
语种	英语
WOS记录号	WOS:000359393800047
资助机构	NSFC ; MOST ; MOE ; LZU
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179053]
专题	基础医学院_期刊论文
通讯作者	Yan, WJ (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Key Lab Preclin Study New Drugs Gansu Prov, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Zhu, YY,Li, XY,Chen, Q,et al. Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes[J]. ORGANIC LETTERS,2015,17(15):3826-3829.
APA	Zhu, YY.,Li, XY.,Chen, Q.,Su, JH.,Jia, FJ.,...&Yan, WJ .(2015).Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes.ORGANIC LETTERS,17(15),3826-3829.
MLA	Zhu, YY,et al."Highly Enantioselective Cascade Reaction Catalyzed by Squaramides: the Synthesis of CF3-Containing Chromanes".ORGANIC LETTERS 17.15(2015):3826-3829.