Centromere repositioning in cucurbit species: Implication of the genomic impact from centromere activation and inactivation

doi:10.1073/pnas.0904833106

	Centromere repositioning in cucurbit species: Implication of the genomic impact from centromere activation and inactivation
	Han, Yonghua 1,2; Zhang, Zhonghua 3; Liu, Chunxia 1; Liu, Jinhua 1; Huang, Sanwen 3; Jiang, Jiming 4; Jin, Weiwei 1
刊名	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
	2009
卷号	106 期号:35 页码:14937-14941
关键词	cucumber melon pericentromeric heterochromatin
ISSN号	0027-8424
DOI	10.1073/pnas.0904833106
通讯作者	Han, Yonghua
英文摘要	The centromere of an eukaryotic chromosome can move to a new position during evolution, which may result in a major alteration of the chromosome morphology and karyotype. This centromere repositioning phenomenon has been extensively documented in mammalian species and was implicated to play an important role in mammalian genome evolution. Here we report a centromere repositioning event in plant species. Comparative fluorescence in situ hybridization mapping using common sets of fosmid clones between two pairs of cucumber (Cucumis sativus L.) and melon (Cucumis melo L.) chromosomes revealed changes in centromere positions during evolution. Pachytene chromosome analysis revealed that the current centromeres of all four cucumber and melon chromosomes are associated with distinct pericentromeric heterochromatin. Interestingly, inactivation of a centromere in the original centromeric region was associated with a loss or erosion of its affixed pericentromeric heterochromatin. Thus, both centromere activation and inactivation in cucurbit species were associated with a gain/loss of a large amount of pericentromeric heterochromatin.
学科主题	Multidisciplinary Sciences ; MULTIDISCIPLINARY SCIENCES
语种	英语
出版者	NATL ACAD SCIENCES
WOS记录号	WOS:000269481000038
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/101203]
专题	蔬菜花卉研究所_生物技术研究室
作者单位	1.China Agr Univ, Beijing Key Lab Crop Genet Improvement, Key Lab Crop Genet Improvement & Genome, Natl Maize Improvement Ctr China,Minist Agr, Beijing 100094, Peoples R China 2.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Cell & Chromosome Engn, Beijing 100101, Peoples R China 3.Chinese Acad Agr Sci, Inst Vegetables & Flowers, Sino Dutch Joint Lab Hort Genom Technol, Key Lab Hort Crops Genet Improvement,Minist Agr, Beijing 100081, Peoples R China 4.Univ Wisconsin, Dept Hort, Madison, WI 53706 USA
推荐引用方式 GB/T 7714	Han, Yonghua,Zhang, Zhonghua,Liu, Chunxia,et al. Centromere repositioning in cucurbit species: Implication of the genomic impact from centromere activation and inactivation[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2009,106(35):14937-14941.
APA	Han, Yonghua.,Zhang, Zhonghua.,Liu, Chunxia.,Liu, Jinhua.,Huang, Sanwen.,...&Jin, Weiwei.(2009).Centromere repositioning in cucurbit species: Implication of the genomic impact from centromere activation and inactivation.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,106(35),14937-14941.
MLA	Han, Yonghua,et al."Centromere repositioning in cucurbit species: Implication of the genomic impact from centromere activation and inactivation".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106.35(2009):14937-14941.