Divergence in function and expression of the NOD26-like intrinsic proteins in plants

doi:10.1186/1471-2164-10-313

CORC > 中国农业科学院 > 蔬菜花卉研究所

	Divergence in function and expression of the NOD26-like intrinsic proteins in plants
	Liu, Qingpo 1; Wang, Huasen 1; Zhang, Zhonghua 2; Wu, Jiasheng 3; Feng, Ying 4; Zhu, Zhujun 1
刊名	BMC GENOMICS
	2009
卷号	10 页码:-
ISSN号	1471-2164
DOI	10.1186/1471-2164-10-313
通讯作者	Liu, Qingpo
英文摘要	Background: NOD26-like intrinsic proteins (NIPs) that belong to the aquaporin superfamily are plant-specific and exhibit a similar three-dimensional structure. Experimental evidences however revealed that functional divergence should have extensively occurred among NIP genes. It is therefore intriguing to further investigate the evolutionary mechanisms being responsible for the functional diversification of the NIP genes. To better understand this process, a comprehensive analysis including the phylogenetic, positive selection, functional divergence, and transcriptional analysis was carried out.Results: The origination of NIPs could be dated back to the primitive land plants, and their diversification would be no younger than the emergence time of the moss P. patens. The rapid proliferation of NIPs in plants may be primarily attributed to the segmental chromosome duplication produced by polyploidy and tandem duplications. The maximum likelihood analysis revealed that NIPs should have experienced strong selective pressure for adaptive evolution after gene duplication and/or speciation, prompting the formation of distinct NIP groups. Functional divergence analysis at the amino acid level has provided strong statistical evidence for shifted evolutionary rate and/or radical change of the physiochemical properties of amino acids after gene duplication, and DIVERGE2 has identified the critical amino acid sites that are thought to be responsible for the divergence for further investigation. The expression of plant NIPs displays a distinct tissue-, cell-type-, and developmental specific pattern, and their responses to various stress treatments are quite different also. The differences in organization of cis-acting regulatory elements in the promoter regions may partially explain their distinction in expression.Conclusion: A number of analyses both at the DNA and amino acid sequence levels have provided strong evidences that plant NIPs have suffered a high divergence in function and expression during evolution, which is primarily attributed to the strong positive selection or a rapid change of evolutionary rate and/or physiochemical properties of some critical amino acid sites.
学科主题	Biotechnology & Applied Microbiology ; Genetics & Heredity ; BIOTECHNOLOGY & APPLIED MICROBIOLOGY ; GENETICS & HEREDITY
语种	英语
出版者	BIOMED CENTRAL LTD
WOS记录号	WOS:000269507000002
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/101988]
专题	蔬菜花卉研究所
作者单位	1.Zhejiang Forestry Univ, Sch Agr & Food Sci, Hangzhou 311300, Zhejiang, Peoples R China 2.Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100081, Peoples R China 3.Zhejiang Forestry Univ, Sch Forestry & Biotechnol, Hangzhou 311300, Zhejiang, Peoples R China 4.Zhejiang Univ, Coll Environm & Resources Sci, Hangzhou 310029, Zhejiang, Peoples R China
推荐引用方式 GB/T 7714	Liu, Qingpo,Wang, Huasen,Zhang, Zhonghua,et al. Divergence in function and expression of the NOD26-like intrinsic proteins in plants[J]. BMC GENOMICS,2009,10:-.
APA	Liu, Qingpo,Wang, Huasen,Zhang, Zhonghua,Wu, Jiasheng,Feng, Ying,&Zhu, Zhujun.(2009).Divergence in function and expression of the NOD26-like intrinsic proteins in plants.BMC GENOMICS,10,-.
MLA	Liu, Qingpo,et al."Divergence in function and expression of the NOD26-like intrinsic proteins in plants".BMC GENOMICS 10(2009):-.