Synthesis and Biological Activities of 1,2,3-Thiadiazole Derivatives Containing 1,3,4-Thiadiazole Moiety

doi:10.6023/cjoc201306002

CORC > 中国农业科学院 > 蔬菜花卉研究所

	Synthesis and Biological Activities of 1,2,3-Thiadiazole Derivatives Containing 1,3,4-Thiadiazole Moiety
	Wang Shouxin 1,2; Zuo Xiang 2; Fan Zhijin 2; Zhang Zhengcai 2; Zhang Jufang 2; Xiong Lixia 2; Fu Yifeng 2; Fang Zhen 2; Wu Qingjun 3; Zhang Youjun 3
刊名	CHINESE JOURNAL OF ORGANIC CHEMISTRY
	2013
卷号	33 期号:11 页码:2367-2375
关键词	1,2,3-thiadiazole 1,3,4-thiadiazole synthesis fungicidal activity insecticidal activity
ISSN号	0253-2786
DOI	10.6023/cjoc201306002
通讯作者	Wang Shouxin
英文摘要	To find novel pesticide lead compounds with highly active bioactivity, 32 novel 1,2,3-thiadiazole derivatives containing 1,3,4-thiadiazole ring were designed and synthesized according to the principle of combination of bioactive substructures. All structures were confirmed by H-1 NMR, IR and HRMS. The fungicidal and insecticidal activities of these compounds were also evaluated. The bioassay results showed that some target compounds had good fungicidal activity and excellent insecticidal activities. Among them, compounds 5-3, 5-20 and 5-31 showed similar insecticidal activity against Plutella xylostella L. as compared with positive control chlorfluazuron at the same condition, compounds 5-6, 5-7, 5-10, 5-14 and 5-17 presented 100% insecticidal activity against Culex pipiens pollen at the concentration of 5 mu g/mL.
学科主题	Chemistry, Organic ; CHEMISTRY, ORGANIC
语种	中文
出版者	SCIENCE PRESS
WOS记录号	WOS:000328597700012
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/101865]
专题	蔬菜花卉研究所
作者单位	1.Jining Med Univ, Sch Basic Sci, Jining 272067, Peoples R China 2.Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China 3.Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100081, Peoples R China
推荐引用方式 GB/T 7714	Wang Shouxin,Zuo Xiang,Fan Zhijin,et al. Synthesis and Biological Activities of 1,2,3-Thiadiazole Derivatives Containing 1,3,4-Thiadiazole Moiety[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2013,33(11):2367-2375.
APA	Wang Shouxin.,Zuo Xiang.,Fan Zhijin.,Zhang Zhengcai.,Zhang Jufang.,...&Zhang Youjun.(2013).Synthesis and Biological Activities of 1,2,3-Thiadiazole Derivatives Containing 1,3,4-Thiadiazole Moiety.CHINESE JOURNAL OF ORGANIC CHEMISTRY,33(11),2367-2375.
MLA	Wang Shouxin,et al."Synthesis and Biological Activities of 1,2,3-Thiadiazole Derivatives Containing 1,3,4-Thiadiazole Moiety".CHINESE JOURNAL OF ORGANIC CHEMISTRY 33.11(2013):2367-2375.