Ubiquitin-Specific Proteases UBP12 and UBP13 Act in Circadian Clock and Photoperiodic Flowering Regulation in Arabidopsis

doi:10.1104/pp.112.213009

	Ubiquitin-Specific Proteases UBP12 and UBP13 Act in Circadian Clock and Photoperiodic Flowering Regulation in Arabidopsis
	Cui, Xia 1; Lu, Falong 1; Li, Yue 2; Xue, Yongming 1,3; Kang, Yanyuan 1,3; Zhang, Shuaibin 1,3; Qiu, Qi 1,3; Cui, Xiekui 1,3; Zheng, Shuzhi 1; Liu, Bin 4
刊名	PLANT PHYSIOLOGY
	2013
卷号	162 期号:2 页码:897-906
ISSN号	0032-0889
DOI	10.1104/pp.112.213009
通讯作者	Cui, Xia
英文摘要	Protein ubiquitination is involved in most cellular processes. In Arabidopsis (Arabidopsis thaliana), ubiquitin-mediated protein degradation regulates the stability of key components of the circadian clock feedback loops and the photoperiodic flowering pathway. Here, we identified two ubiquitin-specific proteases, UBP12 and UBP13, involved in circadian clock and photoperiodic flowering regulation. Double mutants of ubp12 and ubp13 display pleiotropic phenotypes, including early flowering and short periodicity of circadian rhythms. In ubp12 ubp13 double mutants, CONSTANS (CO) transcript rises earlier than that of wild-type plants during the day, which leads to increased expression of FLOWERING LOCUS T. This, and analysis of ubp12 co mutants, indicates that UBP12 and UBP13 regulate photoperiodic flowering through a CO-dependent pathway. In addition, UBP12 and UBP13 regulate the circadian rhythm of clock genes, including LATE ELONGATED HYPOCOTYL, CIRCADIAN CLOCK ASSOCIATED1, and TIMING OF CAB EXPRESSION1. Furthermore, UBP12 and UBP13 are circadian controlled. Therefore, our work reveals a role for two deubiquitinases, UBP12 and UBP13, in the control of the circadian clock and photoperiodic flowering, which extends our understanding of ubiquitin in daylength measurement in higher plants.
学科主题	Plant Sciences ; PLANT SCIENCES
语种	英语
出版者	AMER SOC PLANT BIOLOGISTS
WOS记录号	WOS:000319819900028
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/5037]
专题	作物科学研究所_分子生物学系
作者单位	1.Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China 2.Hebei Normal Univ, Coll Biol Sci, Hebei Key Lab Mol Cell Biol, Shijiazhuang 050016, Hebei, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 4.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China
推荐引用方式 GB/T 7714	Cui, Xia,Lu, Falong,Li, Yue,et al. Ubiquitin-Specific Proteases UBP12 and UBP13 Act in Circadian Clock and Photoperiodic Flowering Regulation in Arabidopsis[J]. PLANT PHYSIOLOGY,2013,162(2):897-906.
APA	Cui, Xia.,Lu, Falong.,Li, Yue.,Xue, Yongming.,Kang, Yanyuan.,...&Cao, Xiaofeng.(2013).Ubiquitin-Specific Proteases UBP12 and UBP13 Act in Circadian Clock and Photoperiodic Flowering Regulation in Arabidopsis.PLANT PHYSIOLOGY,162(2),897-906.
MLA	Cui, Xia,et al."Ubiquitin-Specific Proteases UBP12 and UBP13 Act in Circadian Clock and Photoperiodic Flowering Regulation in Arabidopsis".PLANT PHYSIOLOGY 162.2(2013):897-906.