Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing

doi:10.1186/1471-2164-14-579

	Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing
	Li, Ying-hui 1; Zhao, Shan-cen 2; Ma, Jian-xin 3; Li, Dong 2; Yan, Long 1,4; Li, Jun 2; Qi, Xiao-tian 1; Guo, Xiao-sen 2; Zhang, Le 1; He, Wei-ming 2
刊名	BMC GENOMICS
	2013
卷号	14 页码:-
关键词	Artificial selection Evolution Genetic diversity Population genomics Soybean
ISSN号	1471-2164
DOI	10.1186/1471-2164-14-579
通讯作者	Li, Ying-hui
英文摘要	Background: Artificial selection played an important role in the origin of modern Glycine max cultivars from the wild soybean Glycine soja. To elucidate the consequences of artificial selection accompanying the domestication and modern improvement of soybean, 25 new and 30 published whole-genome re-sequencing accessions, which represent wild, domesticated landrace, and Chinese elite soybean populations were analyzed.Results: A total of 5,102,244 single nucleotide polymorphisms (SNPs) and 707,969 insertion/deletions were identified. Among the SNPs detected, 25.5% were not described previously. We found that artificial selection during domestication led to more pronounced reduction in the genetic diversity of soybean than the switch from landraces to elite cultivars. Only a small proportion (2.99%) of the whole genomic regions appear to be affected by artificial selection for preferred agricultural traits. The selection regions were not distributed randomly or uniformly throughout the genome. Instead, clusters of selection hotspots in certain genomic regions were observed. Moreover, a set of candidate genes (4.38% of the total annotated genes) significantly affected by selection underlying soybean domestication and genetic improvement were identified.Conclusions: Given the uniqueness of the soybean germplasm sequenced, this study drew a clear picture of human-mediated evolution of the soybean genomes. The genomic resources and information provided by this study would also facilitate the discovery of genes/loci underlying agronomically important traits.
学科主题	Biotechnology & Applied Microbiology ; Genetics & Heredity ; BIOTECHNOLOGY & APPLIED MICROBIOLOGY ; GENETICS & HEREDITY
语种	英语
出版者	BIOMED CENTRAL LTD
WOS记录号	WOS:000324210500002
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/5009]
专题	作物科学研究所_分子生物学系
作者单位	1.Chinese Acad Agr Sci, Inst Crop Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Key Lab Germplasm Utilizat MOA, Beijing 100081, Peoples R China 2.BGI Shenzhen, Shenzhen Key Lab Trans Biotechnol, Shenzhen 518083, Peoples R China 3.Purdue Univ, Dept Agron, W Lafayette, IN 47907 USA 4.Hebei Acad Agr & Forestry Sci, Inst Cereal & Oil Crops, Natl Ctr Soybean Improvement, Key Lab Crop Genet & Breeding, Shijiazhuang 050031, Peoples R China 5.Univ Copenhagen, Dept Biol, Copenhagen, Denmark 6.Chinese Acad Sci, Natl Ctr Plant Res, Inst Genet & Dev Biol, State Key Lab Plant & Chromosome Engn, Beijing, Peoples R China 7.Univ Calif Berkeley, Dept Integrat Biol, Berkeley, CA 94820 USA 8.Univ Calif Berkeley, Dept Stat, Berkeley, CA 94820 USA 9.Univ Arkansas, Dept Crop Soil & Environm Sci, Fayetteville, AR 72701 USA 10.Northeast Agr Univ, Chinese Minist Educ, Key Lab Soybean Biol, Harbin 150030, Peoples R China
推荐引用方式 GB/T 7714	Li, Ying-hui,Zhao, Shan-cen,Ma, Jian-xin,et al. Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing[J]. BMC GENOMICS,2013,14:-.
APA	Li, Ying-hui.,Zhao, Shan-cen.,Ma, Jian-xin.,Li, Dong.,Yan, Long.,...&Qiu, Li-juan.(2013).Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing.BMC GENOMICS,14,-.
MLA	Li, Ying-hui,et al."Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing".BMC GENOMICS 14(2013):-.