A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice

doi:10.1038/nbt.3069

	A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice
	Liu, Yuqiang 1; Wu, Han 1; Chen, Hong 1; Liu, Yanling 1; He, Jun 1; Kang, Haiyan 1; Sun, Zhiguang 1; Pan, Gen 1; Wang, Qi 1; Hu, Jinlong 1
刊名	NATURE BIOTECHNOLOGY
	2015
卷号	33 期号:3 页码:301-+
ISSN号	1087-0156
DOI	10.1038/nbt.3069
通讯作者	Liu, Yuqiang
英文摘要	The brown planthopper (BPH) is the most destructive pest of rice (Oryza sativa) and a substantial threat to rice production, causing losses of billions of dollars annually(1,2). Breeding of resistant cultivars is currently hampered by the rapid breakdown of BPH resistance(2). Thus, there is an urgent need to identify more effective BPH-resistance genes. Here, we report molecular cloning and characterization of Bph3, a locus in rice identified more than 30 years ago that confers resistance to BPH. We show that Bph3 is a cluster of three genes encoding plasma membrane-localized lectin receptor kinases (OsLecRK1-OsLecRK3). Introgression of Bph3 into susceptible rice varieties by transgenic or marker-assisted selection strategies significantly enhanced resistance to both the BPH and the white back planthopper. Our results suggest that these lectin receptor kinase genes function together to confer broad-spectrum and durable insect resistance and provide a resource for molecular breeding of insect-resistant rice cultivars.
学科主题	Biotechnology & Applied Microbiology
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000350766900028
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/4751]
专题	作物科学研究所_种质资源保存与研究中心
作者单位	1.Nanjing Agr Univ, Jiangsu Plant Gene Engn Res Ctr, Natl Key Lab Crop Genet & Germplasm Enhancement, Nanjing, Jiangsu, Peoples R China 2.Chinese Acad Agr Sci, Inst Crop Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Beijing 100193, Peoples R China
推荐引用方式 GB/T 7714	Liu, Yuqiang,Wu, Han,Chen, Hong,et al. A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice[J]. NATURE BIOTECHNOLOGY,2015,33(3):301-+.
APA	Liu, Yuqiang.,Wu, Han.,Chen, Hong.,Liu, Yanling.,He, Jun.,...&Wan, Jianmin.(2015).A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice.NATURE BIOTECHNOLOGY,33(3),301-+.
MLA	Liu, Yuqiang,et al."A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice".NATURE BIOTECHNOLOGY 33.3(2015):301-+.