Evolution of a protein domain interaction network_

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	Evolution of a protein domain interaction network_
	Gao Lifeng 1; Shi Jianjun 2; Guan Shan 2
刊名	Chinese Physics. B
	2010
卷号	19 期号:1 页码:010512-1-010512-8
关键词	complex network protein domain network evolution
ISSN号	1674-1056
英文摘要	In this paper, we attempt to understand complex network evolution from the underlying evolutionary relationship between biological organisms. Firstly, we construct a Pfam domain interaction network for each of the 470 completely sequenced organisms, and therefore each organism is correlated with a specific Pfam domain interaction network; secondly, we infer the evolutionary relationship of these organisms with the nearest neighbour joining method; thirdly, we use the evolutionary relationship between organisms constructed in the second step as the evolutionary course of the Pfam domain interaction network constructed in the first step. This analysis of the evolutionary course shows: (i) there is a conserved sub-network structure in network evolution; in this sub-network, nodes with lower degree prefer to maintain their connectivity invariant, and hubs tend to maintain their role as a hub is attached preferentially to new added nodes; (ii) few nodes are conserved as hubs; most of the other nodes are conserved as one with very low degree; (iii) in the course of network evolution, new nodes are added to the network either individually in most cases or as clusters with relative high clustering coefficients in a very few cases.
学科主题	物理学
语种	英语
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/106158]
专题	作物科学研究所
作者单位	1.Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081 2.College of Physics Science and Technology, Yangzhou University, Yangzhou, 225002
推荐引用方式 GB/T 7714	Gao Lifeng,Shi Jianjun,Guan Shan. Evolution of a protein domain interaction network_[J]. Chinese Physics. B,2010,19(1):010512-1-010512-8.
APA	Gao Lifeng,Shi Jianjun,&Guan Shan.(2010).Evolution of a protein domain interaction network_.Chinese Physics. B,19(1),010512-1-010512-8.
MLA	Gao Lifeng,et al."Evolution of a protein domain interaction network_".Chinese Physics. B 19.1(2010):010512-1-010512-8.