海洋二聚吡咯-咪唑类生物碱 | |
王珏 ; 詹岳雄 ; 姜标 | |
刊名 | 化学进展 |
2011 | |
卷号 | 23期号:10页码:2065-2078 |
ISSN号 | 1005-281X |
其他题名 | Dimeric Pyrrole-Imidazole Alkaloids |
通讯作者 | 姜标 |
英文摘要 | Over the last two decades, numerous dimeric pyrrole-imidazole alkaloids have been isolated from marine sponges, and exhibit exciting bioactivities. This may lead to new ideas for biomimetic total synthesis of this group of natural molecules even in advance of their identification and characterization. The interest of organic chemists in the total synthesis of the pyrrole-imidazole alkaloids has strongly increased because of their structural novelty, molecular diversity, and promising biological activities. Challenges are also plentiful from a synthetic point of view. Architectural complexity, unusually high nitrogen content (N/C approximate to 1 : 2), unknown absolute stereochemistry are just some of the dreadful aspects one has to take into account while planning a total synthesis of these alkaloids. This article will account for the recent progress in achieving the total synthesis of these pyrrole-imidazole dimers. |
学科主题 | 天然产物有机化学 |
收录类别 | SCI |
语种 | 中文 |
公开日期 | 2013-02-25 |
内容类型 | 期刊论文 |
源URL | [http://202.127.28.38/handle/331003/20287] |
专题 | 上海有机化学研究所_中科院天然产物有机化学重点实验室 |
推荐引用方式 GB/T 7714 | 王珏,詹岳雄,姜标. 海洋二聚吡咯-咪唑类生物碱[J]. 化学进展,2011,23(10):2065-2078. |
APA | 王珏,詹岳雄,&姜标.(2011).海洋二聚吡咯-咪唑类生物碱.化学进展,23(10),2065-2078. |
MLA | 王珏,et al."海洋二聚吡咯-咪唑类生物碱".化学进展 23.10(2011):2065-2078. |
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