QQ客服 官方微博 反馈留言

	Preparation and characterization of folate-targeted chitosan nanoparticles loaded with hydroxycamptothecin
	Wang, Yixiao ; Hou, Zhenqing ; Cui, Fei ; Shen, Lihua ; Xie, Liya ; Zhang, QiQing ; Yi, Yunfeng ; Hou ZQ(侯振清) ; Zhang QQ(张其清)
	2012
关键词	Characterization Chitosan Crosslinking Drug delivery Emulsification Encapsulation Loading Nanoparticles Organic acids X ray powder diffraction Zeta potential
英文摘要	Conference Name:2nd International Conference on Chemical Engineering and Advanced Materials, CEAM 2012. Conference Address: Guangzhou, China. Time:July 13, 2012 - July 15, 2012.; FA-targeted and 10-hydroxycamptothecin loaded chitosan nanoparticles (FA-HCPT-NPs) were prepared with a combination of emulsion-solvent evaporation and chemical crosslink method. The analysis revealed that the FA-HCPT-NPs were spherical with diameter of 255.5 卤 16.2 nm, zeta potential of + 70 mV, HCPT encapsulation efficiency of 81.2% and loading rate of 2.5%. X-ray powder diffraction illustrated that HCPT was buried as an amorphous form in the NPs. The release profiles of HCPT exhibited a biphasic pattern characterized by an initial burst release followed by a slower and sustained release. The results indicated that the novel FA-HCPT-NPs could be a potential drug delivery system for tumor cell-selective targeting therapy. 漏 (2012) Trans Tech Publications, Switzerland.
语种	英语
出处	http://dx.doi.org/10.4028/www.scientific.net/AMR.557-559.434
出版者	TRANS TECH PUBLICATIONS LTD
内容类型	其他
源URL	[http://dspace.xmu.edu.cn/handle/2288/85137]
专题	材料学院－会议论文
推荐引用方式 GB/T 7714	Wang, Yixiao,Hou, Zhenqing,Cui, Fei,et al. Preparation and characterization of folate-targeted chitosan nanoparticles loaded with hydroxycamptothecin. 2012-01-01.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。