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题名	Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepatotoxicity
作者	MUNZIR MOHAMED ELHAG AHMED
答辩日期	2011 ; 1900
导师	杨云青
关键词	AKR7A aflatoxin aldehyde reductase Acetaminophen cell death Nrf2
英文摘要	Aldo-keto reductase-7A (AKR7A) is an enzyme important for bioactivation and biodetoxification. Previous studies suggested that Akr7a might be transcriptionally regulated by oxidative stress-responsive transcription factor Nrf2, a protein highly responsive to acetaminophen (APAP) or its intermediate metabolite N-acetyl-p-benzoquinoneimine (NAPQI). This study was therefore carried out to inv...; 学位：理学博士; 院系专业：生命科学学院生物学系_生物化学与分子生物学; 学号：21720070154137
语种	zh_CN
出处	http://210.34.4.13:8080/lunwen/detail.asp?serial=29331
内容类型	学位论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/46120]
专题	生命科学－学位论文
推荐引用方式 GB/T 7714	MUNZIR MOHAMED ELHAG AHMED. Aldo-keto reductase-7A protects liver cells and tissues from acetaminophen-induced oxidative stress and hepatotoxicity[D]. 2011, 1900.

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