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	Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid
	Zhu, Yu-Jing ; Tang, Jian-Yang ( Fujian Acad Agr Sci) ; Su, Ming-Xing ( Fujian Acad Agr Sci) ; Liu, Bo( Fujian Acad Agr Sci) ; Zhou, Han-Tao ; Zhou HT(周涵韬) ; Hu, Yong-Hua ; Guo, Yun-Ji ; Chen, Qing-Xi ; Chen QX(陈清西)
	2010-06-16
关键词	2-Phenylethanol 2-Phenylacetaldehyde 2-Phenylacetic acid Antityrosinase activity Antimicrobial activity
英文摘要	The inhibition kinetics of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid on the enzyme activity of mushroom tyrosinase have been investigated. The results showed that these aromatic compounds can lead to reversible inhibition of the enzyme; furthermore, 2-phenylacetaldehyde and 2-phenylacetic acid are uncompetitive inhibitors and 2-phenylethanol is a mixed-type inhibitor. The inhibition constants have been determined and the inhibiting ability was: 2-phenylacetaldehyde > 2-phenylacetic acid > 2-phenylethanol, indicating that the functional group on the benzene ring group played an important role in the inhibition of the enzyme. In addition, 2-phenylacetic acid and 2-phenylethanol were found to have effective antibacterial activities, and 2-phenylacetic acid was more effective against Escherichia coli and Ralstonia solanacearum than 2-phenylethanol, but 2-phenylacetaldehyde lacked of antibacterial activity. (C) 2010 Elsevier Ltd. All rights reserved.; National High Technology Research and Development Program ("863" Program) of China[2006AA10A211]; Natural Science Foundation of China[30570408, 20832005, 30871667]; Science and Technology Foundation of Fujian Province[2007N0051, 2009R10037]; Program for New Century Excellent Talents in Fujian Province University; Postdoctoral Foundation of China[20080430787]
语种	中文
出版者	ELSEVIER SCI LTD
内容类型	期刊论文
源URL	[http://dx.doi.org/doi:10.1016/j.foodchem.2010.06.036]
专题	生命科学－会议论文
推荐引用方式 GB/T 7714	Zhu, Yu-Jing,Tang, Jian-Yang ,Su, Ming-Xing ,et al. Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid[J],2010.
APA	Zhu, Yu-Jing.,Tang, Jian-Yang .,Su, Ming-Xing .,Liu, Bo.,Zhou, Han-Tao.,...&陈清西.(2010).Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid..
MLA	Zhu, Yu-Jing,et al."Antityrosinase and antimicrobial activities of 2-phenylethanol, 2-phenylacetaldehyde and 2-phenylacetic acid".(2010).

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