Chemoselective Cascade Synthesis of N-Fused Heterocycles via Silver(I) Triflate-Catalyzed Friedel-Crafts/N-C Bond Formation Sequence

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	Chemoselective Cascade Synthesis of N-Fused Heterocycles via Silver(I) Triflate-Catalyzed Friedel-Crafts/N-C Bond Formation Sequence
	Hao, Lu ; Pan, Yingming ; Wang, Tao ; Lin, Min ; Chen, Li ; Zhan, Zhuang-ping ; Chen L(陈亮)
刊名	http://dx.doi.org/10.1002/adsc.201000525
	2010-12-17
关键词	ONE-POT SYNTHESIS FECL3-CATALYZED NUCLEOPHILIC-SUBSTITUTION AZIDE CYCLOADDITION CHEMISTRY PROPARGYLIC ALCOHOLS AROMATIC-COMPOUNDS TANDEM REACTION DERIVATIVES INDOLES CATIONS FURANS
英文摘要	National Natural Science Foundation of China [20772098, 21072159]; An efficient cascade methodology toward chemoselective synthesis of N-fused heterocycles including 9H-pyrrolo[1,2-a] indole, 3H-pyrrolo[1,2-a]indole and 1H-pyrrolo[1,2-a]indole derivatives has been developed. This transformation proceeds via a silver(I) triflate-catalyzed consecutive Friedel-Crafts reaction/N-C bond formation sequence between readily available propargyl alcohols and 3-substituted 1H-indoles. Not only is excellent chemoselectivity observed according to the substitution patterns of propargyl alcohols, but also the Lewis acid-catalyzed N-C bond formation process can be carried out under base- and ligand-free conditions.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/65567]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Hao, Lu,Pan, Yingming,Wang, Tao,et al. Chemoselective Cascade Synthesis of N-Fused Heterocycles via Silver(I) Triflate-Catalyzed Friedel-Crafts/N-C Bond Formation Sequence[J]. http://dx.doi.org/10.1002/adsc.201000525,2010.
APA	Hao, Lu.,Pan, Yingming.,Wang, Tao.,Lin, Min.,Chen, Li.,...&陈亮.(2010).Chemoselective Cascade Synthesis of N-Fused Heterocycles via Silver(I) Triflate-Catalyzed Friedel-Crafts/N-C Bond Formation Sequence.http://dx.doi.org/10.1002/adsc.201000525.
MLA	Hao, Lu,et al."Chemoselective Cascade Synthesis of N-Fused Heterocycles via Silver(I) Triflate-Catalyzed Friedel-Crafts/N-C Bond Formation Sequence".http://dx.doi.org/10.1002/adsc.201000525 (2010).