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	H-1 and C-13 NMR signal assignments of Paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp (tree 1-7)
	Guo, Zhiyong（Zhongshan Univ, Sch Chem & Chem Engn） ; She, Zhigang（Zhongshan Univ, Sch Chem & Chem Engn） ; Shao, Changlun（Zhongshan Univ, Sch Chem & Chem Engn） ; Wen, Lu（Zhongshan Univ, Sch Chem & Chem Engn） ; Liu, Fan（Zhongshan Univ, Sch Chem & Chem Engn） ; Zheng, Zhonghui ; Zheng ZH(郑忠辉) ; Lin, Yongcheng（Zhongshan Univ, Sch Chem & Chem Engn）
	2007
关键词	NMR H-1 NMR C-13 NMR paecilin A paecilin B
英文摘要	Two new natural products, named paecilin A (1) and B (2), together with two known compounds secalonic acid D (3) and (11)-cytochalasa-6(12),13-diene-1,21-dione-16,18-dimethyl-7-hydroxy-10-phenyl-(7S*,13E,16S*,18S*) (4), were isolated from the mangrove endophytic fungus, Paecilomyces sp. (tree 1-7) from the South China Sea. 1D and 2D NMR experiments including COSY, HMQC, and HMBC were used for the determination of their structures. In our cytotoxicity assays, secalonic D (3) showed cytotoxicity toward KB cells with IC50 < 1 mu g ml(-1) and inhibiting human topoisomerase I with IC50 at 0.16 mu mol ml(-1).1, 2, and 4 showed no activity to KB cells. Copyright (C) 2007 John Wiley & Sons, Ltd.
语种	英语
出版者	JOHN WILEY & SONS LTD
内容类型	期刊论文
源URL	[http://dx.doi.org/doi:10.1002/mrc.2035]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Guo, Zhiyong,She, Zhigang,Shao, Changlun,et al. H-1 and C-13 NMR signal assignments of Paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp (tree 1-7)[J],2007.
APA	Guo, Zhiyong.,She, Zhigang.,Shao, Changlun.,Wen, Lu.,Liu, Fan.,...&Lin, Yongcheng.(2007).H-1 and C-13 NMR signal assignments of Paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp (tree 1-7)..
MLA	Guo, Zhiyong,et al."H-1 and C-13 NMR signal assignments of Paecilin A and B, two new chromone derivatives from mangrove endophytic fungus Paecilomyces sp (tree 1-7)".(2007).

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