Combined PEG immobilization on polystyrene microspheres: Ability of protein resistance | |
Xiao, Xifeng ; Zhou, Leiji ; Zhou LJ(周雷激) | |
2012 | |
关键词 | Chain length Chemical engineering Microspheres Polyethylene glycols Polystyrenes Proteins |
英文摘要 | Conference Name:2nd International Conference on Chemical Engineering and Advanced Materials, CEAM 2012. Conference Address: Guangzhou, China. Time:July 13, 2012 - July 15, 2012.; Polyethylene glycol (PEG) fixation has been proved to significantly decrease nonspecific protein adsorption on varied substrates. Here, a strategy of surface modification using two kinds of PEGs with different chain lengths was developed to improve the surface ability of protein resistance. We designed different reaction routes and investigated their reaction conditions. The amount of nonspecific protein adsorption on the substrates after modification was measured by UV-Vis spectrometry. The results showed that higher performance of protein resistance on the solid surface was acquired from the two-step modification than other methods. A competitive mechanism of reaction was proposed to elucidate the interaction between distinct PEGs on the substrates. 漏 (2012) Trans Tech Publications, Switzerland. |
语种 | 英语 |
出处 | http://dx.doi.org/10.4028/www.scientific.net/AMR.550-553.1214 |
出版者 | TRANS TECH PUBLICATIONS LTD |
内容类型 | 其他 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/85426] |
专题 | 化学化工-会议论文 |
推荐引用方式 GB/T 7714 | Xiao, Xifeng,Zhou, Leiji,Zhou LJ. Combined PEG immobilization on polystyrene microspheres: Ability of protein resistance. 2012-01-01. |
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