| 高效液相色谱-质谱联用技术在海洋药用生物化学成分快速鉴别中的应用; Applications of HPLC-MS in the Rapid Identification of Components in Marine Medicinal Organisms | |
| 张道来 ; 陈军辉 ; 周明 ; 黎先春 ; 王小如 | |
| 2010 | |
| 关键词 | 高效液相色谱-质谱联用 海洋药用生物 快速鉴别 high performance liquid chromatography-mass spectrometry marine medicinal organisms rapid identification |
| 英文摘要 | 高效液相色谱-质谱联用(HPlC-MS)技术,将HPlC的高分离效能与MS的强大结构鉴定功能结合起来,已逐渐成为天然产物化学成分快速分离、鉴别的强有力手段。本研究采用高效液相色谱-电喷雾质谱联用(HPlC-ESI-MS)技术,成功建立了刺参皂苷快速鉴别方法,并对市售干刺参中的4种皂苷进行了鉴别。此外,应用该技术对罗氏海盘车中的13种化学成分进行了快速鉴别。为海洋药用生物化学成分快速鉴别提供了1种值得推广的新方法,为更好的开发利用海洋天然药物奠定了基础。; In recent years,high performance liquid chromatography-mass spectrometry combined the high separation efficiency of HPLC with rapid identification function of MS had become a powerful tool for the rapid separation and identification of chemical components in natural products.In the present study,a high performance liquid chromatography-electrospray ionization mass spectrometry(HPLC-ESI-MS) method was developed for rapid identification of 4 saponin components in dry Holothurian sold on the market.On the other hand,13 compounds in Asterias rollestoni were also identified by HPLC-ESI-MS.The HPLC-MS method presented in this paper for the rapid identification of marine compounds was worth popularizing and to lay a foundation for the further exploration of marine natural products.; 国家自然科学基金项目(20675021;20905017);中国近海海洋综合调查与评价908专项项目(908-02-05-04);海洋局青年基金资助 |
| 语种 | zh_CN |
| 内容类型 | 期刊论文 |
| 源URL | [http://dspace.xmu.edu.cn/handle/2288/106344]  |
| 专题 | 化学化工－已发表论文 |
| 推荐引用方式 GB/T 7714 | 张道来,陈军辉,周明,等. 高效液相色谱-质谱联用技术在海洋药用生物化学成分快速鉴别中的应用, Applications of HPLC-MS in the Rapid Identification of Components in Marine Medicinal Organisms[J],2010. |
| APA | 张道来,陈军辉,周明,黎先春,&王小如.(2010).高效液相色谱-质谱联用技术在海洋药用生物化学成分快速鉴别中的应用.. |
| MLA | 张道来,et al."高效液相色谱-质谱联用技术在海洋药用生物化学成分快速鉴别中的应用".(2010). |
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