A universal and multiplex kinase assay using gamma-[O-18(4)]-ATP

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	A universal and multiplex kinase assay using gamma-[O-18(4)]-ATP
	Fu, Chuan ; Zheng, Xueyun ; Jiang, Yao ; Liu, Yan ; Xu, Pengxiang ; Zeng, Zhiping ; Liu, Rihe ; Zhao, Yufen ; Liu Y(刘艳) ; Xu PX(许鹏翔) ; Ceng ZP(曾志平) ; Zhao YF(赵玉芬)
刊名	http://dx.doi.org/10.1039/c3cc38467e
	2013
关键词	DEPENDENT PROTEIN-KINASE SCINTILLATION PROXIMITY ASSAY ELECTROCHEMICAL DETECTION MASS-SPECTROMETRY PHOSPHORYLATION FLUORESCENCE CELLS INHIBITORS SUBSTRATE PROBES
英文摘要	State Key Development Program for Basic Research of China [2013CB910700, 2012CB821600]; NSFC [21075103]; We have synthesized gamma-[O-18(4)]-ATP and used it to develop a non-radioactive and multiplex method. Significantly, this novel approach can be applied to any kinases without using a purified enzyme or a fluorescent substrate. Using this approach, the effectiveness and specificity of inhibitors on several kinases could be readily determined.
语种	英语
出版者	ROYAL SOC CHEMISTRY
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/88816]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Fu, Chuan,Zheng, Xueyun,Jiang, Yao,et al. A universal and multiplex kinase assay using gamma-[O-18(4)]-ATP[J]. http://dx.doi.org/10.1039/c3cc38467e,2013.
APA	Fu, Chuan.,Zheng, Xueyun.,Jiang, Yao.,Liu, Yan.,Xu, Pengxiang.,...&赵玉芬.(2013).A universal and multiplex kinase assay using gamma-[O-18(4)]-ATP.http://dx.doi.org/10.1039/c3cc38467e.
MLA	Fu, Chuan,et al."A universal and multiplex kinase assay using gamma-[O-18(4)]-ATP".http://dx.doi.org/10.1039/c3cc38467e (2013).