Antifouling activities of hymenialdisine and debromohymenialdisine from the sponge Axinella sp

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	Antifouling activities of hymenialdisine and debromohymenialdisine from the sponge Axinella sp
	Feng, Dan Qing ; Qiu, Yan ; Wang, Wei ; Wang, Xiang ; Ouyang, Peng Gang ; Ke, Cai Huan ; Feng DQ(冯丹青) ; Qiu Y(邱彦) ; Wang W(王玮) ; Ke CH(柯才焕)
刊名	http://dx.doi.org/10.1016/j.ibiod.2013.08.014
	2013
关键词	MARINE NATURAL-PRODUCTS CHEMICAL DEFENSE LARVAE INVERTEBRATES METABOLITES INHIBITION ATTACHMENT ORGANISMS COMPOUND EXTRACTS
英文摘要	National Natural Science Foundation of China [41276127]; Public Science and Technology Research Funds Projects of Ocean of China [201305016]; Natural Science Foundation of Fujian Province of China [2011J01276]; Fundamental Research Funds for the Central Universities of China [2010111025, 2011121056]; Being physically unprotected sessile organisms, marine sponges are thought to protect themselves from surface fouling through the use of antifouling secondary metabolites. In this study, the sponge Axinella sp. was extracted with methanol and then partitioned between organic solvents and water. Two main compounds, hymenialdisine (HD) and debromohymenialdisine (DBH), were isolated from the n-BuOH layer using Sephadex LH-20 and C-18 column chromatography. The antifouling activity of HD and DBH were evaluated using the test of byssus thread production with the green mussel Perna viridis, and the settlement assays with the bryozoan Bugula neritina larvae and the green alga Ulva prolifera spores. Both HD and DBH were found to exhibit significant antifouling activities against P. viridis (EC50 values of 31.77 and 138.18 mu g ml(-1), respectively), B. neritina (EC50 values of 3.43 and 8.17 mu g ml(-1), respectively) and U. prolifera (EC50 values of 8.31 and 0.67 mu g ml(-1), respectively). Our results suggested that HD and DBH may play a role in chemical defense against fouling in Axinella sp. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.
语种	英语
出版者	ELSEVIER SCI LTD
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/87938]
专题	海洋环境－已发表论文
推荐引用方式 GB/T 7714	Feng, Dan Qing,Qiu, Yan,Wang, Wei,et al. Antifouling activities of hymenialdisine and debromohymenialdisine from the sponge Axinella sp[J]. http://dx.doi.org/10.1016/j.ibiod.2013.08.014,2013.
APA	Feng, Dan Qing.,Qiu, Yan.,Wang, Wei.,Wang, Xiang.,Ouyang, Peng Gang.,...&柯才焕.(2013).Antifouling activities of hymenialdisine and debromohymenialdisine from the sponge Axinella sp.http://dx.doi.org/10.1016/j.ibiod.2013.08.014.
MLA	Feng, Dan Qing,et al."Antifouling activities of hymenialdisine and debromohymenialdisine from the sponge Axinella sp".http://dx.doi.org/10.1016/j.ibiod.2013.08.014 (2013).