| 植物抗病毒分子机制 | |
| 钱礼超 ; 刘玉乐 ; QIAN LiChao ; LIU YuLe | |
| 2016-03-30 ; 2016-03-30 | |
| 关键词 | 植物抗病毒 RNA沉默 R基因 植物-病毒互作 S432.1 |
| 其他题名 | Molecular Mechanism of Plant Antiviral Defense |
| 中文摘要 | 在与植物病毒的长期斗争中,植物进化出多种抗病毒机制,其中RNA沉默和R基因介导的病毒抗性是最受人们关注的两种机制.一方面,RNA沉默是植物抵抗病毒侵染的重要手段.植物在病毒侵染过程中可形成病毒来源的双链RNA,经过DCL蛋白的切割、加工形成sRNA,与AGO蛋白结合形成RISC指导病毒RNA的沉默,用于清除病毒.相应地,病毒在与植物的竞争中进化出RNA沉默抑制子,抑制宿主RNA沉默系统以逃避宿主RNA沉默抗病毒反应,增强致病能力.另一方面,植物也进化出R基因介导植物对包括病毒在内的多类病原的抗性.R蛋白直接或间接识别病毒因子,通过一系列的信号转导途径激活植物防御反应,限制病毒的进一步侵染.对植物抗病毒的研究有助于人们对植物抗病分子基础的理解,有重要的科学意义和潜在应用价值.本文综述了植物抗病毒分子机制的重要进展.; During a long coevolutionary arms race between plants and viruses, plants have evolved various antiviral defense mechanisms. Among them, RNA silencing and R gene-mediated virus resistance attract more attention. On the one hand, RNA silencing plays an important role in plant resistance against viruses. During virus infection, virus-derived double stranded RNAs can be formed and processed into small RNAs to target viral RNAs for destruction. Accordingly, viruses have evolved to produce RNA silencing suppressors to overcome host RNA silencing and enhance virus infection. On the other hand, plants have also evolved R gene-mediated resistance to various pathogens including viruses. Research on plant antiviral defense will help understanding of the molecular basis of plant disease resistance, and will have important scientific significance and potential application value. This manuscript reviews the important advances in molecular plant antiviral defense mechanisms. |
| 语种 | 中文 ; 中文 |
| 内容类型 | 期刊论文 |
| 源URL | [http://ir.lib.tsinghua.edu.cn/ir/item.do?handle=123456789/148471]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | 钱礼超,刘玉乐,QIAN LiChao,等. 植物抗病毒分子机制[J],2016, 2016. |
| APA | 钱礼超,刘玉乐,QIAN LiChao,&LIU YuLe.(2016).植物抗病毒分子机制.. |
| MLA | 钱礼超,et al."植物抗病毒分子机制".(2016). |
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