| 反射波增强指数与动脉硬化指标相关性的研究 | |
| 刘严 ; 齐丽彤 ; 马为 ; 杨颖 ; 孟磊 ; 张宝娓 ; 霍勇 ; Liu Yan ; Qi Litong ; Ma Wei ; Yang Ying ; Meng Lei ; Zhang Baowei ; Huo Yong | |
| 2016-03-30 ; 2016-03-30 | |
| 关键词 | 血管 反射波增强指数 动脉硬化 Blood vessels Augmentation index(AI) Atherosclerosis R543.5 |
| 其他题名 | The association between augmentation index and arterial stiffness index |
| 中文摘要 | 目的探讨反射波增强指数(AI)与肱-踝动脉脉搏波传导速度(baPWV)之间的相关性及其影响因素。方法选择2010年4-6月北京市石景山区首钢地区参与调查研究的社区居民1 752例,年龄23~90岁,平均(59.82±11.88)岁。应用科林HEM-9000AI检测仪测量AI,科林无创动脉硬化测定仪VP-1000测量baPWV及踝臂指数(ABI),彩色多普勒超声仪采集双侧颈动脉图像,测量双侧颈动脉内-中膜厚度(IMT)。结果 ABI≤0.9组与ABI﹥0.9组、IMT≥0.9 mm组与IMT﹤0.9 mm组比较,baPWV差异均有统计学意义(P﹤0.05),而AI75(心率为75次/min时的标准校正值)的组间差异无统计学意义。AI与baPWV低度相关(r=-0.068,P=0.005);多因素回归分析显示,性别、年龄、体质指数、腰臀比、心率、ABI和收缩压是AI的相关因素。结论 AI的相关影响因素较多,且与baPWV的相关性较差,不能单独作为评价动脉僵硬度的敏感、可靠指标。; Objective To explore the association between arterial system augmentation index(AI) and brachial-ankle pulse wave velocity(baPWV). Methods All subjects were selected from a local community. The study included 1 752 people living in Shijingshan district, Beijing during April to June,2010. Subjects whose age ranged from 23 to 90 years old [(59.82 ±11.88) years old] were included and 56.7% of the subjects were women. Pulse wave at the left radial artery was measured and the AI was calculated by Colin pulse wave detection device HEM9000AI. baPWV and ankle-brachial index(ABI) were measured using Colin noninvasive arteriosclerosis tester VP-1000. Color doppler flow imaging was used to measure intima-media thickness(IMT) of the bilateral carotid artery. Results The baPWV was significantly higher in ABI≤0.9 group and IMT≥0.9 mm group, while there was no significant difference of AI75between groups. AI had a low correlation with baPWV(r =-0.068, P = 0.005). Partial correlation analysis showed that there was no significant association between AI and baPWV(r =-0.033, P = 0.17). In multiple stepwise regression analysis, the factors of AI included gender, age, BMI, waist-to-hip ratio, heart rate, ABI and systolic pressure. Conclusion No significant correlation can be found between AI and baPWV. Various factors may influence the measurement of AI. This study suggests that AI may not be a sensitive and reliable index for the evaluation of arterial stiffness. |
| 语种 | 中文 ; 中文 |
| 内容类型 | 期刊论文 |
| 源URL | [http://ir.lib.tsinghua.edu.cn/ir/item.do?handle=123456789/147209]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | 刘严,齐丽彤,马为,等. 反射波增强指数与动脉硬化指标相关性的研究[J],2016, 2016. |
| APA | 刘严.,齐丽彤.,马为.,杨颖.,孟磊.,...&Huo Yong.(2016).反射波增强指数与动脉硬化指标相关性的研究.. |
| MLA | 刘严,et al."反射波增强指数与动脉硬化指标相关性的研究".(2016). |
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