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	A method of temperature measurement using low field MRIs with a 3D steady-state free precession pulse sequence
	Sui Yi ; Zhao Lei ; Gao Xiao-Rong ; Gao Shang-Kai
	2010-10-12 ; 2010-10-12
关键词	Theoretical or Mathematical Experimental/ biomedical MRI biothermics medical signal processing radiation therapy temperature measurement tumours/ temperature measurement method low field MRI 3D steady state free precession pulse sequence temperature change monitoring thermoablation tumor treatment 3D-SSFP magnetic field inhomogeneity optimum flip angles relaxation time uncertainty/ A8760I Medical magnetic resonance imaging and spectroscopy A8770H Radiation therapy A8716 Biothermics B7510N Biomedical magnetic resonance imaging and spectroscopy B7520C Radiation therapy B7320R Thermal variables measurement B6140 Signal processing and detection
中文摘要	MRI can be used to monitor the temperature changes during a thermoablation treatment of tumors. 3D steady-state free precession sequence (3D-SSFP) can be used for temperature mapping in the low field scanner. However, conventional SSFP method using single acquisition is highly sensitive to the inhomogeneity of the main magnetic field. In this study a method using multi-acquisition combination with high and low flip angles was proposed to improve the imaging tolerability to the inhomogeneity. The linear relationship between the temperature and the normalized signal was analyzed by simulation. The optimum flip angles were calculated to get the best tolerability to the inhomogeneity, and the system bias introduced by the uncertainty of relaxation time T/sub 1/ and T/sub 2/ was discussed. The results from simulation and experiments at 0.45 T permanent MRI scanner showed the feasibility of the proposed method. Comparing with single acquisition method, multi-acquisition combination method has equivalent temperature linearity, less sensitivity to the heterogeneity of the main magnetic field and less system bias. The imaging time for each temperature map with the new method is 6 s, which is suitable for the clinical applications.
语种	中文
出版者	Chinese Society of Biomedical Engineering ; China
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/78670]
专题	清华大学
推荐引用方式 GB/T 7714	Sui Yi,Zhao Lei,Gao Xiao-Rong,et al. A method of temperature measurement using low field MRIs with a 3D steady-state free precession pulse sequence[J],2010, 2010.
APA	Sui Yi,Zhao Lei,Gao Xiao-Rong,&Gao Shang-Kai.(2010).A method of temperature measurement using low field MRIs with a 3D steady-state free precession pulse sequence..
MLA	Sui Yi,et al."A method of temperature measurement using low field MRIs with a 3D steady-state free precession pulse sequence".(2010).

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