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	丹参与藜芦配伍化学成分变化的UPLC/Q-TOF研究
	夏锦明 ; 孟宪生 ; 张颖 ; 张敏 ; XIA Jin-ming ; MENG Xian-sheng ; ZHANG Ying ; ZHANG Min
	2010-07-15 ; 2010-07-15
会议名称	第十五届全国分子光谱学术报告会 ; CNKI
关键词	丹参 藜芦 配伍 质谱 Salvia miltiorrhiza Bge Veratrum nigrum L Combination MS R284
其他题名	Studies on the Variation of Chemical Constituents During the Combination of Salvia Miltiorrhiza with Veratrum Nigrum by UPLC/Q-TOF
中文摘要	采用超高效液相与飞行时间质谱连用技术,对丹参与藜芦配伍过程中化学成分的变化规律进行研究,在丹参与藜芦配伍共煎液中共确定七种成分,其中两种丹参中没有藜芦含有分子量分别为752.3921,694.3934的化合物,在丹参与藜芦配伍共煎液中含量显著增加;一种丹参与藜芦共同含有分子量为464.3294的化合物,在丹参与藜芦配伍共煎液中含量显著增加;其中三种丹参中没有藜芦含有分子量分别为710.3897,752.3979,694.3934的化合物,在丹参与藜芦配伍共煎液中含量显著降低;一种丹参与藜芦共同含有分子量为99.0701的化合物,在丹参与藜芦配伍共煎液中含量显著降低,丹参与藜芦配伍后藜芦所含成分发生了变化,所以丹参反藜芦具有一定道理。; The variation of chemical constituents during the combination of Salvia miltiorrhiza Bge with Veratrum nigrum L was investrgated by Ultra High Performance Liquid Chromatography/Time of Flight Mass Spectrometry (UPLC/Q-TOF).In the compatible decoction,seven components were detected.The contents of the two with the MW (molecular weight) of 752.392 1 and 694.393 4 were found in Veratrum nigrurn L while not in Salvia miltiorrhiza Bge and the one with the MW of 464.329 4 which was found in both Veratrum nigrum L and Salvia miltiorrhiza Bge increased significantly.The contents of another three with the MW of 710.389 7.752.397 9 and 694.393 4,which were found in Veratrum nigrum L while not in Salvia miltiorrhiza Bge and another one with the MW of 99.070 1,which was found in both Veratrum nigrum L and Salvia miltiorrhiza Bge de- creased significantly.From the chemical point of view,the chemical constituents in Veratrum nigrum L changed after combina- tion with the Salvia miltiorrhiza Bge,so the traditional theory is right that Salvia mihiorrhiza Bge and Veratrum nigrum L are in- compatible each other.
会议录出版者	北京大学出版社
语种	中文 ; 中文
内容类型	会议论文
源URL	[http://hdl.handle.net/123456789/68579]
专题	清华大学
推荐引用方式 GB/T 7714	夏锦明,孟宪生,张颖,等. 丹参与藜芦配伍化学成分变化的UPLC/Q-TOF研究[C]. 见:第十五届全国分子光谱学术报告会, CNKI.

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