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	In vitro aging of mineralized collagen-based composite as guided tissue regeneration membrane
	Pan, SX ; Li, Y ; Feng, HL ; Bai, W ; Gu, YY
	2010-05-10 ; 2010-05-10 ; OCT 04-06, 2004
会议名称	MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS ; 2nd Asia Symnposium on Biomineralization ; Beijing, PEOPLES R CHINA ; Web of Science
关键词	guided tissue regeneration (GTR) nano-hydroxyapatite collagen in vitro aging SCAFFOLDS CULTURE ACID) Materials Science, Multidisciplinary
中文摘要	The technique of guided tissue regeneration (GTR) has been developed for the regeneration of periodontal tissues, bone around natural teeth and dental implants. The aim of this study is to investigate the biodegradability and mechanic behavior of a novel mineralized nanohydroxyapatite/collagen/poly (lactic acid) (nHAC/PLA) composite as GTR membrane in vitro. The elastic modulus and maximum tensile strength of GTR film samples with different nHAC/PLA ratio were measured to get an optimal nHAC/PLA ratio. Thermogravimetric analysis was conducted to evaluate the change of the inorganic component in the samples during the process of in vitro aging. Morphology of samples was checked by using scanning electron microscopy. On the basis of the above results, it can be concluded that the GTR membranes maintained integrity and the original appearance throughout the 1-month in vitro aging. There is an active dissolution and deposition process of crystals which is propitious to the bone formation on the surface of the composite membrane. The optimal nHAC/PLA ratio of the novel membrane is 0.4:1. For a longer period of bone repair, PLA with higher molecular weight should be chosen as the scaffold for the GTR membrane. (c) 2005 Elsevier B.V. All rights reserved.; Tsinghau Univ
会议录出版者	ELSEVIER SCIENCE BV ; AMSTERDAM ; PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
语种	英语 ; 英语
内容类型	会议论文
源URL	[http://hdl.handle.net/123456789/18289]
专题	清华大学
推荐引用方式 GB/T 7714	Pan, SX,Li, Y,Feng, HL,et al. In vitro aging of mineralized collagen-based composite as guided tissue regeneration membrane[C]. 见:MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2nd Asia Symnposium on Biomineralization, Beijing, PEOPLES R CHINA, Web of Science.

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