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	Condensation effect of cholesterol, stigmasterol, and sitosterol on dipalmitoylphosphatidylcholine in molecular monolayers
	Su, Yunlan ; Li, Qingzhong ; Chen, Lin ; Yu, Zhiwu
	2010-05-06 ; 2010-05-06
关键词	condensation effect cholesterol stigmasterol sitosterol monolayer DIFFERENTIAL SCANNING CALORIMETRY AIR-WATER-INTERFACE MODEL MEMBRANES LIPID RAFTS STEROL STRUCTURE PLASMA-MEMBRANE DETERGENT SOLUBILITY PHASE-EQUILIBRIA DOMAINS COMPRESSIBILITY Chemistry, Physical
中文摘要	The effects of the incorporation of cholesterol, sitosterol, and stigmasterol into dipalmitoylphosphatidylcholine (DPPC) monolayers were investigated by Langmuir monolayer film technique in this study. The compressibility coefficient was assessed at various surface pressures. The observations indicated that sitosterol and stigmasterol interacted less effectively than cholesterol with the phospholipid. Nevertheless, these sterol molecules could all cause condensation effect on DPPC monolayers. Attractive interactions between DPPC and sterol molecules, or hydrophobic effect, was found to play an important role, testified by negative excess molecular areas at particularly low surface pressures and negative partial molecular area of three sterols at low surface pressures. The minimum extreme points for the excess area were all located at around 0.3 mol fractions for the three sterols at 30 mN/m, which suggest a 2:1 ratio of DPPC/sterol in the ordered structures. (c) 2006 Elsevier B.V. All rights reserved.
语种	英语 ; 英语
出版者	ELSEVIER SCIENCE BV ; AMSTERDAM ; PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/12807]
专题	清华大学
推荐引用方式 GB/T 7714	Su, Yunlan,Li, Qingzhong,Chen, Lin,et al. Condensation effect of cholesterol, stigmasterol, and sitosterol on dipalmitoylphosphatidylcholine in molecular monolayers[J],2010, 2010.
APA	Su, Yunlan,Li, Qingzhong,Chen, Lin,&Yu, Zhiwu.(2010).Condensation effect of cholesterol, stigmasterol, and sitosterol on dipalmitoylphosphatidylcholine in molecular monolayers..
MLA	Su, Yunlan,et al."Condensation effect of cholesterol, stigmasterol, and sitosterol on dipalmitoylphosphatidylcholine in molecular monolayers".(2010).

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