Synthesis of Rupestonic Acid Derivatives with Antiviral Activity

CORC > 新疆理化技术研究所 > 中国科学院新疆理化技术研究所 > 省部共建新疆特有药用资源利用重点实验室

	Synthesis of Rupestonic Acid Derivatives with Antiviral Activity
	Zhao, JY (Zhao, Jiangyu); Niu, C (Niu, Chao); Li, G (Li, Gen); Aisa, HA (Aisa, Haji Akber)
刊名	CHEMISTRY OF NATURAL COMPOUNDS
	2017
卷号	53 期号:2 页码:276-283
通讯作者	Aisa, HA
英文摘要	A series of 23 new rupestonic acid derivatives were synthesized. Their activities against influenza viruses A (H3N2, H1N1) and B were studied. Compounds 2d and 2g demonstrated potent activity against influenza virus A (H3N2) with IC50 values of 0.35 and 0.21 mu M, respectively. Compound 5g (n = 10) was the most potent compound of this series against influenza viruses H3N2 and H1N1 with IC50 values of 2.89 and 0.38 mu M. Several of the synthesized compounds were weakly active against influenza virus B and were more toxic than starting rupestonic acid.
收录类别	SCI
WOS记录号	WOS:000400195700017
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/4783]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室新疆理化技术研究所_资源化学研究室
作者单位	1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China
推荐引用方式 GB/T 7714	Zhao, JY ,Niu, C ,Li, G ,et al. Synthesis of Rupestonic Acid Derivatives with Antiviral Activity[J]. CHEMISTRY OF NATURAL COMPOUNDS,2017,53(2):276-283.
APA	Zhao, JY ,Niu, C ,Li, G ,&Aisa, HA .(2017).Synthesis of Rupestonic Acid Derivatives with Antiviral Activity.CHEMISTRY OF NATURAL COMPOUNDS,53(2),276-283.
MLA	Zhao, JY ,et al."Synthesis of Rupestonic Acid Derivatives with Antiviral Activity".CHEMISTRY OF NATURAL COMPOUNDS 53.2(2017):276-283.