Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose
Zhou, Wei1,2,3; Zhuang, Yibin1,2; Bai, Yanfen1,2,3; Bi, Huiping1,2; Liu, Tao1,2; Ma, Yanhe1
刊名MICROBIAL CELL FACTORIES
2016-08-30
卷号15
关键词Isovaleryl-CoA Phlorisovalerophenone 4-Hydroxy-6-isobutyl-2-pyrone Valerophenone synthase Escherichia coli
英文摘要Background: Type III polyketide synthases (PKSs) contribute to the synthesis of many economically important natural products, which are typically produced by direct extraction from plants or synthesized chemically. For example, humulone and lupulone (Fig. 1a) in hops (Humulus lupulus) account for the characteristic bitter taste of beer and display multiple pharmacological effects. 4-Hydroxy-6-methyl-2-pyrone is a precursor of parasorboside contributing to insect and disease resistance of plant Gerbera hybrida, and was recently demonstrated to be a potential platform chemical.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biotechnology & Applied Microbiology
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]TRIACETIC ACID LACTONE ; HOP HUMULUS-LUPULUS ; III POLYKETIDE SYNTHASE ; HYPERICUM-PERFORATUM ; SACCHAROMYCES-CEREVISIAE ; MEVALONATE PATHWAY ; BITTER ACIDS ; L. ; PHLOROGLUCINOL ; DERIVATIVES
收录类别SCI
语种英语
WOS记录号WOS:000382463900001
内容类型期刊论文
源URL[http://124.16.173.210/handle/834782/2920]  
专题天津工业生物技术研究所_天然化合物合成生物学实验室 刘涛_期刊论文
作者单位1.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China
2.Chinese Acad Sci, Key Lab Syst Microbial Biotechnol, Tianjin 300308, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhou, Wei,Zhuang, Yibin,Bai, Yanfen,et al. Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose[J]. MICROBIAL CELL FACTORIES,2016,15.
APA Zhou, Wei,Zhuang, Yibin,Bai, Yanfen,Bi, Huiping,Liu, Tao,&Ma, Yanhe.(2016).Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose.MICROBIAL CELL FACTORIES,15.
MLA Zhou, Wei,et al."Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose".MICROBIAL CELL FACTORIES 15(2016).
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