Ultrasmall CuCo2S4 Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 生物材料与组织工程研究中心 > 期刊论文

	Ultrasmall CuCo2S4 Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors
	Li, Bo 1,2; Yuan, Fukang 1,3; He, Guanjie 4; Han, Xiaoyu 4; Wang, Xin 1; Qin, Jinbao 1; Guo, Zheng Xiao 4; Lu, Xinwu 1; Wang, Qian 5; Parkin, Ivan P.4
刊名	ADVANCED FUNCTIONAL MATERIALS
	2017-03-10
卷号	27 期号:10
关键词	CuCo2S4 nanocrystals DFT calculations photothermal therapy ternary bimetal chalcogenides ultrasmall magnetic resonance imaging
英文摘要	Copper-based ternary bimetal chalcogenides have very promising potential as multifunctional theragnosis nanoplatform for photothermal treatment of tumors. However, the design and synthesis of such an effective platform remains challenging. In this study, hydrophilic CuCo2S4 nanocrystals (NCs) with a desirable size of approximate to 10 nm are synthesized by a simple one-pot hydrothermal route. The as-prepared ultrasmall CuCo2S4 NCs show: 1) intense near-infrared absorption, which is attributed to 3d electronic transitions from the valence band to an intermediate band, as identified by density functional theory calculations; 2) high photothermal performance with a photothermal conversion efficiency up to 73.4%; and 3) capability for magnetic resonance (MR) imaging, as a result of the unpaired 3d electrons of cobalt. Finally, it is demonstrated that the CuCo2S4 NCs are a promising all-in-one photothermal theragnosis nanoplatform for photothermal cancer therapy under the irradiation of a 915 nm laser at a safe power density of 0.5 W cm(-2), guided by MR and infrared thermal imaging. This work further promotes the potential applications of ternary bimetal chalcogenides for photothermal theragnosis therapy.
WOS标题词	Science & Technology ; Physical Sciences ; Technology
类目[WOS]	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
关键词[WOS]	980 NM LASER ; QUANTUM DOTS ; CONVERSION EFFICIENCY ; CANCER-CELLS ; FE5C2 NANOPARTICLES ; FACILE SYNTHESIS ; RENAL CLEARANCE ; BRILLOUIN-ZONE ; SPECIAL POINTS ; AGENT
收录类别	SCI
语种	英语
WOS记录号	WOS:000395717600018
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/23564]
专题	上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文
作者单位	1.Shanghai Jiao Tong Univ, Dept Vasc Surg, Sch Med, Shanghai Peoples Hosp 9, Shanghai 200011, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 3.Xuzhou Cent Hosp, Dept Vasc Surg, Xuzhou 221009, Jiangsu, Peoples R China 4.UCL, Dept Chem, Christopher Ingold Lab, London WC1H 0AJ, England 5.Shanghai Jiao Tong Univ, Dept Orthopaed, Shanghai Peoples Hosp 1, Shanghai 200080, Peoples R China
推荐引用方式 GB/T 7714	Li, Bo,Yuan, Fukang,He, Guanjie,et al. Ultrasmall CuCo2S4 Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors[J]. ADVANCED FUNCTIONAL MATERIALS,2017,27(10).
APA	Li, Bo.,Yuan, Fukang.,He, Guanjie.,Han, Xiaoyu.,Wang, Xin.,...&Wu, Chengtie.(2017).Ultrasmall CuCo2S4 Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors.ADVANCED FUNCTIONAL MATERIALS,27(10).
MLA	Li, Bo,et al."Ultrasmall CuCo2S4 Nanocrystals: All-in-One Theragnosis Nanoplatform with Magnetic Resonance/Near-Infrared Imaging for Efficiently Photothermal Therapy of Tumors".ADVANCED FUNCTIONAL MATERIALS 27.10(2017).